Preclinical and Clinical Trials
Roche
It can take years to determine which drug regimen or drug cocktail is the best for a given patient population. At Roche, we use MathWorks tools to model the safety and efficacy of drugs and optimize dose scheduling, which greatly improves the efficiency of a drug's transition from preclinical to clinical trials.
Additional Resources
- Webinar: Computational Statistics in BioPharm Using MATLAB Products
- Webinar: Quantitative High-Throughput Gene Expression Imaging
- Webinar: Response Surface Models of Drug Interactions
- Webinar: Introduction to Curve Fitting for Nonprogrammers
- Biotech and Pharmaceutical Overview
- Preclinical Research and Development
- Preclinical and Clinical Trials
- Pharmaceutical Manufacturing
Researchers use MathWorks tools to evaluate drug safety, dosage, and effectiveness in preclinical and clinical research. In one flexible, customizable platform, researchers implement the entire workflow from modeling to analysis, including ADME and nonlinear mixed-effects (NLME) modeling.
SimBiology®, the MathWorks pharmacokinetics and pharmacodynamics (PK/PD) modeling environment, provides point-and-click tools that make PK/PD modeling and analysis accessible even for researchers with little or no programming experience. Researchers can access an industry-tested simulation solver suite, and integrate PK/PD modeling with other functionality such as parallel computing, statistics, and optimization.
When using MathWorks tools in clinical research, scientists can leverage capabilities such as database integration and report generation to help meet regulatory guidelines.
Learn more about MathWorks products for computational biology.
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