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| R2012a Documentation → Bioinformatics Toolbox | |
Learn more about Bioinformatics Toolbox |
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| Contents | Index |
This table summarizes what's new in Version 3.3 (R2009a):
| New Features and Changes | Version Compatibility Considerations | Fixed Bugs and Known Problems |
|---|---|---|
| Yes Details below | Yes—Details labeled as Compatibility Considerations, below. See also Summary. | Bug
Reports Includes fixes |
New and updated features in this version include:
Following is a new function:
microplateplot — Display visualization of microtiter plate.
The following functions are updated:
rebasecuts — Find restriction enzymes that cut nucleotide sequence. Updated to use Version 811 of REBASE, the Restriction Enzyme Database.
restrict — Split nucleotide sequence at restriction site. Updated to use Version 811 of REBASE, the Restriction Enzyme Database.
The following function is updated:
nt2aa — Convert nucleotide sequence to amino acid sequence. Updated to include a new property, 'ACGTOnly', to support ambiguous and unknown nucleotide characters.
The following functions are updated to use with data from any separation technique, including mass spectrometry:
msalign — Align peaks in signal to reference peaks.
msbackadj — Correct baseline of signal with peaks.
mslowess — Smooth signal with peaks using nonparametric method.
msnorm — Normalize set of signals with peaks.
mspeaks — Convert raw peak data to peak list (centroided data).
msppresample — Resample signal with peaks while preserving peaks.
msresample — Resample signal with peaks.
mssgolay — Smooth signal with peaks using least-squares polynomial.
The following functions are updated:
cghcbs — Perform circular binary segmentation (CBS) on array-based comparative genomic hybridization (aCGH) data. Updated to include an optional heuristic stopping rule to improve performance.
ilmnbslookup — Look up Illumina® BeadStudio™ target (probe) sequence and annotation information. Updated to read Illumina microRNA array annotation files.
ilmnbsread — Read gene expression data exported from Illumina BeadStudio software. Updated to read Illumina microRNA array data files.
mattest — Perform two-sample t-test to evaluate differential expression of genes from two experimental conditions or phenotypes. Updated with new property, 'VarType', which lets you specify equal or unequal (default) variance for the test.
A compatibility consideration related to the mattest function was introduced in Bioinformatics Toolbox Version 3.2, but not reported in the Release Notes for Version 3.2 (R2008b). Specifically, in Bioinformatics Toolbox Version 3.1 and earlier, the mattest function used equal variance for the test. In Bioinformatics Toolbox Version 3.2, the mattest function starting using unequal variance for the test.
The following is a new sequence analysis demo:
| Predicting Protein Secondary Structure Using a Neural Network |
 | Version 3.4 (R2009b) Bioinformatics Toolbox Software | Version 3.2 (R2008b) Bioinformatics Toolbox Software |  |
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