5.0 | 2 ratings Rate this file 363 downloads (last 30 days) File Size: 4.81 KB File ID: #12705

Clinical Test Performance

19 Oct 2006 (Updated 07 Oct 2009)

The test calculate the performance of a clinical test based on the Bayes theorem

File Information
Description	This function calculate the performance, based on Bayes theorem, of a clinical test. The input is based on a 2x2 matrix (true positive, false positives; false negative, true negatives). The Outputs are: - Prevalence of disease - Test Sensibility with 95% confidence interval - Test Specificity with 95% confidence interval - False positive and negative proportions - Youden's Index - Matthews Correlation Coefficient - Number needed to Diagnose (NDD) - Discriminant Power - Test Accuracy - Mis-classification Rate - Positive predictivity with 95% confidence interval - Negative predictivity with 95% confidence interval - Positive Likelihood Ratio - Negative Likelihood Ratio - Test bias - Diagnostic odds ratio - Error odds ratio
MATLAB release	MATLAB 7.1.0 (R14SP3)
Zip File Content
Other Files	license.txt, partest.m

Tags for This File
Everyone's Tags	bayes theorem(2), biotech(2), clinical test performance, pharmaceutical(2), sensibility, specificity
Tags I've Applied
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Comments and Ratings (2)
11 Mar 2007	catalin001@k.ro mihai
10 Oct 2009	Jan Simon	Exhaustively commented, so you get not only the resulting numbers, but also the exact description of what they mean, if you read the source.

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Updates
23 Oct 2006	Improvement in the first line
23 Oct 2006	fix in errors messages
23 Oct 2006	Fix bug in the first line
30 Oct 2006	Error handling improvements
05 Jul 2007	Youden's index and Discriminant Power added
18 Aug 2007	Added new outputs
30 Apr 2008	minor bugs correction
20 May 2008	Matthews Correlation Coefficient added
12 Nov 2008	Changes in help section
15 Dec 2008	Added a plot of the main results
09 Feb 2009	Mistake correction in discrimination power formula (Thank you Prof. Hans Winkler!)
27 Jul 2009	confidence interval for sensibility and specificity added
29 Jul 2009	Added new 95% confidence intervals for positive and negative predictive values
07 Oct 2009	Help section was updated; computations are more efficient and output is more rational. Statistics are fully detailed.

Tag Activity for this File
Tag	Applied By	Date/Time
biotech	Giuseppe Cardillo	22 Oct 2008 08:44:33
pharmaceutical	Giuseppe Cardillo	22 Oct 2008 08:44:33
clinical test performance	Giuseppe Cardillo	22 Oct 2008 08:44:33
sensibility	Giuseppe Cardillo	22 Oct 2008 08:44:33
bayes theorem	Giuseppe Cardillo	22 Oct 2008 08:44:33
specificity	Giuseppe Cardillo	22 Oct 2008 08:44:33
pharmaceutical	Cristina McIntire	12 Nov 2008 13:56:41
biotech	Cristina McIntire	12 Nov 2008 13:56:45
bayes theorem	Claudio Gelmi	06 Mar 2009 14:28:51

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