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Nodose neuron action potential firing.

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Model of action potential firing by an A-type nodose neuron

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Simulink implementation of nodose neuron action potential firing with parameters from the following studies:

Schild,J.H., Clark,J.W., Hay,M., Mendelowitz,D., Andresen,M.C., and Kunze,D.L. (1994). A- and C-type rat nodose sensory neurons: model interpretations of dynamic discharge characteristics. J. Neurophysiol. 71, 2338-2358.

Schild,J.H., and Kunze,D.L. (1997). Experimental and modeling study of Na+ current heterogeneity in rat nodose neurons and its impact on neuronal discharge. J. Neurophysiol. 78, 3198-3209.

The screenshot image is the response to 0.04 nA current injection from the resting membrane potential at 37C.

Comments and Ratings (2)

juan gomez

quiero verlo

Elena Petroff

An excellent model to test contribution of different ion channels to the shape and frequency of the action potential discharge.

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