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Response Surface Models of Drug Interactions with Curve Fitting Toolbox

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Response Surface Models of Drug Interactions with Curve Fitting Toolbox

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20 Mar 2009 (Updated )

"Response Surface Models of Drug Interactions with Curve Fitting Toolbox" webinar demo files

combinedEffect(CA, CB, IC50A, IC50B, alpha, n)
function Effect = combinedEffect(CA, CB, IC50A, IC50B, alpha, n)

% Copyright 2009, The MathWorks, Inc.

% Effect is normalized to maxEffect. Therefore, assume Emax = 1
Emax = 1;

% Model 
Effect = Emax*( CA/IC50A + CB/IC50B + alpha*( CA/IC50A ) .* ( CB/IC50B ) ).^n          ...
           ./(( CA/IC50A + CB/IC50B + alpha*( CA/IC50A ) .* ( CB/IC50B ) ).^n  + 1     );

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