This GUI is a tool to compute the Paternity Index in a lawsuit for paternity attribution or exclusion. It is possible to use the Applied Biosystems, Promega or Biotype forensic kits. The GUI can be use in presence or in absence of the mother's data. If the alleged father is not available (in case of death) it is possible to setup the procedure using a father's relative. The GUI also has a module for incest lawsuit. Data can be saved and reloaded. Moreover there are several demo and info of the used STRs.
Before to compute PI, the GUI checks if "mater certa est" and if Mother and Child samples were swapped.
Now it computes also reverse parentage: this is the case to adopt in case of kidnapping or suspect baby exchange into the nursery
If you want a flowchart explaining how the code works, it is long as a book and anyway the code is heavly commented so you can look at it.
If you want a flowchart explaining how using GUI, I'm surprised because it is very intuitive for Forensic Genetist and there are several demos.
1) choose the population by popupmenu
2) choose the used kit by popupmenu
3) In the option menu, eventually, choose if it is an incestuous relationship or not; direct or reverse parentage (the last if you are not sure that mother is the mother)
4) choose persecutor and defense hypothesis by their popupmenu
5) insert the alleles
6) push on compute button
7) push on report (if you want) and you will find it into REPORT subdirectory into CODIS
would you please provide the functionality flowchart for this code.
simply do this:
1) in Matlab enter into the directory where you installed CODIS (use the window into the left side)
2) type "CODISpwd=pwd; save CODISpwd.mat CODISpwd; clear CODISpwd"
3) that'all. Anyway I will modify the software.
I find your app very interesting. I downloaded it but when running it I get some errors. It seems that some files are missing.
"load CODISpwd.mat CODISpwd
Can you provide these files?
some improvements in report routines
bug correction in Brenner mutation model in Child-Alleged Father scenario
minor bug correction in reports menu
Bug corrections in DEMO sections; some other minor "make-up"
bug correction in Reverse Parentage results presentation (computation is correct)
Added the reverse parentage subroutine
Promega Powerplex 18 kit was added;
minor bug correction in CODIS3 subroutine
some little improvements into report phase
New format for reports
several little programming improvements.
In the last update, the GUI checks for possible swap of mother-child samples. The alleged father-child swap is not needed because it will show many maternal mismatches.
GUI doesn't show the posterior probability of kinship. You will find in the report a table with posterior probabilities as function of prior odds
Tutankhamun's demo added; STRinfo report added; code sped up.
All power of exclusion menu were split in 3:
All routines were revisited. HTML files are more adherent to WC3 standard. Sibship index was added. GUI for load and save file.
Mean Exclusion Chance added in the Paternity Statistics
Changes in description
A more detailed report is generated. Another little bug was corrected
Bug correction in CODIS3 PItemp computation. Correction in the report creation
Correction of a bug in CODIS3 module
A Report Menu to generate an html report of the results was added
In this version, a module for incest lawsuit was added.
Citation added in the help section
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