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Cryo-EM image simulator

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Cryo-EM image simulator

by Fred Sigworth

 

05 Nov 2011 (Updated 08 Nov 2011)

Creates a density map from atomic coordinates, automatically including the density of solvent.

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Description

In electron cryomicroscopy (cryo-EM) protein molecules embedded in vitreous ice are imaged with an electron microscope. The function SolventAndProteinDensity() models the 3D electron-scattering density of a protein. The special feature is that a continuum model of the surrounding water (ice) is automatically included, which makes the simulation much more realistic. DemoSolvatedMap.m is an example driver script. Please write fsigworth@gmail.com to receive a preprint of a paper describing the algorithm.

MATLAB release MATLAB 7.13 (2011b)
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Updates
08 Nov 2011

Added a note that the reader can contact me for a preprint of the technical description.

Tag Activity for this File
Tag Applied By Date/Time
biotech Fred Sigworth 07 Nov 2011 09:37:22
image processing Fred Sigworth 07 Nov 2011 09:37:22
simulation Fred Sigworth 07 Nov 2011 09:37:22

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