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Using SimBiology for Mechanism-Based PK/PD Modeling in Preclinical & Discovery

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Using SimBiology for Mechanism-Based PK/PD Modeling in Preclinical & Discovery


Fulden (view profile)


11 May 2012 (Updated )

Examples used in the March 2012 webinar: Using SimBiology for Mechanism-Based PK/PD Modeling

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View the recorded webinar here:
In this webinar, you learn how to use SimBiology and MATLAB to implement mechanism-based PK/PD modeling workflows. Using a modeling and simulation case-study from literature, we demonstrate:

• Building mechanism-based PK/PD models using an interactive block-diagram editor
• Estimating parameters by fitting experimental data
• Simulating different dosing strategies
• Exploring system dynamics using parameter sweeps & sensitivity analysis
• Automating and customizing analyses using MATLAB

We also highlight new features in SimBiology 2012a including:

• Simulation Viewer – a interactive visualization tool for model exploration
• Weighted fitting
• Simultaneously fitting data from multiple dose levels

Required Products Curve Fitting Toolbox
Statistics and Machine Learning Toolbox
MATLAB release MATLAB 7.14 (R2012a)
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Comments and Ratings (1)
23 Aug 2016 The Lich

Referenced unit 'CFU' does not exist.

11 May 2012 1.1

Updating files.

01 Sep 2016

Updated license

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