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SimBiology implementation of PBPK model for Trichloroethylene (TCE)

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SimBiology model describing the metabolism and distribution of TCE using a human PBPK model

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This is a SimBiology implementation of a physiologically-based pharmacokinetic (PBPK) model for Trichloroethylene (TCE) and its metabolites as described in the article below:
Fisher, J.W., Mahle, D. and Abbas, R. (1998) A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol. Toxicology and Applied Pharmacology, 152(2), 339-359.

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Damir (view profile)


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