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Renin-Angiotensin-System (RAS) model for SimBiology

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29 Aug 2012 (Updated )

Provides a SimBiology model implementation of the Renin-Angiotensin-System

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Description

The Renin-Angiotensin pathway is crucial for the control of blood pressure. Perturbations of this pathway are involved in a large number of pathological conditions, hypertension being one of them. This SimBiology project contains a model of the Renin-Angiotensin-System as described in reference [1].

References
[1] Lo, A., Beh, J., Leon, H. D., Hallow, M. K., Ramakrishna, R., Rodrigo, M., & Sarkar, A. (2011). Using a Systems Biology Approach to Explore Hypotheses Underlying Clinical Diversity of the Renin Angiotensin System and the Response to Antihypertensive Therapies. (H. H. C. Kimko & C. C. Peck, Eds.) Clinical Trial Simulations, 1, 457-482.

Acknowledgements

Physiologically Based Pharmacokinetic (Pbpk) Model For Sim Biology inspired this file.

Required Products SimBiology
MATLAB
MATLAB release MATLAB 7.14 (R2012a)
Other requirements C Compiler needed for simulation acceleration
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Updates
05 Feb 2013

Updated screenshot and diagram.

07 Feb 2013

screenshot modified

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