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WTSI Mutational Signature Framework

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WTSI Mutational Signature Framework

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23 Oct 2012 (Updated )

Framework for deciphering signatures of mutational processes from a set of mutational catalogues

All files for WTSI Mutational Signature Framework
/data/2012-Nik-ZainalEtAl-Cell/21_WTSI_BRCA_whole_genome_substitutions.mat
/data/2013-AlexandrovEtAl-CellReports/100_WTSI_BRCA_whole_exome_substitutions.mat
/data/2013-AlexandrovEtAl-CellReports/100_WTSI_BRCA_whole_exome_substitutions_strand_bias.mat
/data/2013-AlexandrovEtAl-CellReports/21_WTSI_BRCA_whole_genome_substitutions.mat
/data/2013-AlexandrovEtAl-CellReports/21_WTSI_BRCA_whole_genome_substitutions_dinucleotides_indels_kataegis.mat
/data/2013-AlexandrovEtAl-CellReports/21_WTSI_BRCA_whole_genome_substitutions_pentanucleotides.mat
/data/2013-AlexandrovEtAl-CellReports/21_WTSI_BRCA_whole_genome_substitutions_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/.DS_Store
/data/2013-AlexandrovEtAl-Nature/exomes/ALL/ALL_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/ALL/ALL_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/ALL/ALL_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/AML/AML_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/AML/AML_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/AML/AML_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Bladder/Bladder_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Bladder/Bladder_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Bladder/Bladder_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Breast/Breast_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Breast/Breast_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Breast/Breast_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Cervix/Cervix_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Cervix/Cervix_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Cervix/Cervix_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/CLL/CLL_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/CLL/CLL_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/CLL/CLL_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Colorectum/Colorectum_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Colorectum/Colorectum_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Colorectum/Colorectum_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Esophageal/Esophageal_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Esophageal/Esophageal_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Esophageal/Esophageal_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Glioblastoma/Glioblastoma_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Glioblastoma/Glioblastoma_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Glioblastoma/Glioblastoma_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Glioma Low Grade/Glioma Low Grade_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Glioma Low Grade/Glioma Low Grade_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Glioma Low Grade/Glioma Low Grade_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Head and Neck/Head and Neck_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Head and Neck/Head and Neck_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Head and Neck/Head and Neck_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Chromophobe/Kidney Chromophobe_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Chromophobe/Kidney Chromophobe_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Chromophobe/Kidney Chromophobe_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Clear Cell/Kidney Clear Cell_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Clear Cell/Kidney Clear Cell_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Clear Cell/Kidney Clear Cell_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Papillary/Kidney Papillary_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Papillary/Kidney Papillary_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Kidney Papillary/Kidney Papillary_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Adeno/Lung Adeno_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Adeno/Lung Adeno_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Adeno/Lung Adeno_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Small Cell/Lung Small Cell_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Small Cell/Lung Small Cell_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Small Cell/Lung Small Cell_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Squamous/Lung Squamous_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Squamous/Lung Squamous_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lung Squamous/Lung Squamous_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lymphoma B-cell/Lymphoma B-cell_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lymphoma B-cell/Lymphoma B-cell_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Lymphoma B-cell/Lymphoma B-cell_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Melanoma/Melanoma_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Melanoma/Melanoma_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Melanoma/Melanoma_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Myeloma/Myeloma_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Myeloma/Myeloma_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Myeloma/Myeloma_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Neuroblastoma/Neuroblastoma_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Neuroblastoma/Neuroblastoma_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Neuroblastoma/Neuroblastoma_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Ovary/Ovary_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Ovary/Ovary_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Ovary/Ovary_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Pancreas/Pancreas_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Pancreas/Pancreas_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Pancreas/Pancreas_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Prostate/Prostate_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Prostate/Prostate_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Prostate/Prostate_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Stomach/Stomach_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Stomach/Stomach_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Stomach/Stomach_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Thyroid/Thyroid_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Thyroid/Thyroid_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Thyroid/Thyroid_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Uterus/Uterus_exomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Uterus/Uterus_exomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/exomes/Uterus/Uterus_exomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/ALL/ALL_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/ALL/ALL_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/ALL/ALL_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/AML/AML_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/AML/AML_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/AML/AML_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Breast/Breast_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Breast/Breast_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Breast/Breast_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/CLL/CLL_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/CLL/CLL_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/CLL/CLL_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Liver/Liver_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Liver/Liver_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Liver/Liver_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Lung Adeno/Lung Adeno_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Lung Adeno/Lung Adeno_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Lung Adeno/Lung Adeno_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Lymphoma B-cell/Lymphoma B-cell_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Lymphoma B-cell/Lymphoma B-cell_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Lymphoma B-cell/Lymphoma B-cell_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Medulloblastoma/Medulloblastoma_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Medulloblastoma/Medulloblastoma_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Medulloblastoma/Medulloblastoma_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Pancreas/Pancreas_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Pancreas/Pancreas_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Pancreas/Pancreas_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Pilocytic Astrocytoma/Pilocytic Astrocytoma_genomes_mutational_catalog_192_subs_with_strand_bias.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Pilocytic Astrocytoma/Pilocytic Astrocytoma_genomes_mutational_catalog_96_subs.mat
/data/2013-AlexandrovEtAl-Nature/genomes/Pilocytic Astrocytoma/Pilocytic Astrocytoma_genomes_mutational_catalog_99_subs_with_indels_and_dinucs.mat
/example1.m
/example2.m
/example3.m
/example4.m
/input/100_WTSI_BRCA_whole_exome_substitutions_strand_bias.mat
/input/21_WTSI_BRCA_whole_genome_substitutions.mat
/license.txt
/plotting/plotSamples.m
/plotting/plotSamplesWithStrandBias.m
/plotting/plotSignatures.m
/plotting/plotSignaturesExposureInSamples.m
/plotting/plotSignatureStabilityAndReconstruction.m
/plotting/plotSignaturesWithStrandBias.m
/plotting/rotateticklabel.m
/plotting/rotateticklabelWithColor.m
/plotting/ThousandSep.m
/readme.pdf
/source/addWeak.m
/source/bootstrapCancerGenomes.m
/source/decipherMutationalProcesses.m
/source/deconvolute.m
/source/evaluateStability.m
/source/extract.m
/source/fcnnls.m
/source/filterOutIterations.m
/source/gdcls.m
/source/nmf.m
/source/nmfsh_comb.m
/source/removeWeak.m
/__MACOSX/._data
/__MACOSX/._example1.m
/__MACOSX/._example2.m
/__MACOSX/._example3.m
/__MACOSX/._example4.m
/__MACOSX/._input
/__MACOSX/._output
/__MACOSX/._plotting
/__MACOSX/._source
/__MACOSX/._temp
/__MACOSX/data/2012-Nik-ZainalEtAl-Cell/._21_WTSI_BRCA_whole_genome_substitutions.mat
/__MACOSX/data/2013-AlexandrovEtAl-CellReports/._100_WTSI_BRCA_whole_exome_substitutions.mat
/__MACOSX/data/2013-AlexandrovEtAl-CellReports/._100_WTSI_BRCA_whole_exome_substitutions_strand_bias.mat
/__MACOSX/data/2013-AlexandrovEtAl-CellReports/._21_WTSI_BRCA_whole_genome_substitutions.mat
/__MACOSX/data/2013-AlexandrovEtAl-CellReports/._21_WTSI_BRCA_whole_genome_substitutions_dinucleotides_indels_kataegis.mat
/__MACOSX/data/2013-AlexandrovEtAl-CellReports/._21_WTSI_BRCA_whole_genome_substitutions_pentanucleotides.mat
/__MACOSX/data/2013-AlexandrovEtAl-CellReports/._21_WTSI_BRCA_whole_genome_substitutions_strand_bias.mat
/__MACOSX/data/2013-AlexandrovEtAl-Nature/._.DS_Store
/__MACOSX/input/._100_WTSI_BRCA_whole_exome_substitutions_strand_bias.mat
/__MACOSX/input/._21_WTSI_BRCA_whole_genome_substitutions.mat
/__MACOSX/plotting/._plotSamples.m
/__MACOSX/plotting/._plotSamplesWithStrandBias.m
/__MACOSX/plotting/._plotSignatures.m
/__MACOSX/plotting/._plotSignaturesExposureInSamples.m
/__MACOSX/plotting/._plotSignatureStabilityAndReconstruction.m
/__MACOSX/plotting/._plotSignaturesWithStrandBias.m
/__MACOSX/plotting/._rotateticklabel.m
/__MACOSX/plotting/._rotateticklabelWithColor.m
/__MACOSX/plotting/._ThousandSep.m
/__MACOSX/source/._addWeak.m
/__MACOSX/source/._bootstrapCancerGenomes.m
/__MACOSX/source/._decipherMutationalProcesses.m
/__MACOSX/source/._deconvolute.m
/__MACOSX/source/._evaluateStability.m
/__MACOSX/source/._extract.m
/__MACOSX/source/._fcnnls.m
/__MACOSX/source/._filterOutIterations.m
/__MACOSX/source/._gdcls.m
/__MACOSX/source/._nmf.m
/__MACOSX/source/._nmfsh_comb.m
/__MACOSX/source/._removeWeak.m

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