Try Multiprecision Computing Toolbox from here: http://advanpix.com
It supports 32 and 64-bit versions of Windows and the latest Matlabs. Easily installed in a few seconds, no compilation required - everything are installed and tuned automatically for the best performance on your CPU.
Mas OS X (64-bit) and Linux (32 & 64-bit) are also supported. No compilation is required.
Multiprecision Computing Toolbox from Advanpix supports much wider set of MATLAB functions missing in the submission, including eig, det, cond, fft/ifft, chol, fzero, null to name a few. Many advanced numerical methods are supported too - matrix functions, optimization, ODE, root finding, special functions, numerical integration, etc....
Alternative approach for noise-robust differentiation is described here:
On the contrary to Savitzky-Golay filters it has nice property of guaranteed noise suppression.