image thumbnail

updated 3 months ago

RGDS_Practical_Guide by Daniel/Ronald

MATLAB routines for the book: "Development of Innovative Drugs via Modeling with MATLAB". (simulation, pharmaceutical, simulink)

AUC

CTSbasics.m

DDEconst

image thumbnail

updated 4 months ago

App Builder for SimBiology Models by Asawari Samant

Tool to automate the process of creating standalone, model-exploration apps for SimBiology model (simbiology, pkpd, systems biology)

buildApp(inputSet, compileFlag)

createSlider(f, pNum, pInfo)

createUI(model, appName)

image thumbnail

updated 1 year ago

Renin-Angiotensin-System (RAS) model for SimBiology by Sven Mesecke

Provides a SimBiology model implementation of the Renin-Angiotensin-System (simbiology, pkpd, systems biology)

image thumbnail

updated 1 year ago

Generic SimBiology Physiologically-based Pharmacokinetic (PBPK) model by Sven Mesecke

SimBiology implementation of a generic PBPK model. Human fasted, Human fed and Rat physiologies. (simbiology, simbiology model, pbpk)

calculateParacellularAbsorption(DrugLogP, DrugMolecularWe...

calculateTissuePartition(...

image thumbnail

updated almost 2 years ago

Physiologically-based Pharmacokinetic (PBPK) model for SimBiology by Sven Mesecke

Provides a PBPK and a Renin-Angiotensin system model for SimBiology (simbiology, simbiology model, pbpk)

calculateParacellularAbsorption(DrugLogP, DrugMolecularWe...

calculateTissuePartition(...

image thumbnail

updated 2 years ago

SimBiology implementation of PBPK model for Trichloroethylene (TCE) by Asawari Samant

SimBiology model describing the metabolism and distribution of TCE using a human PBPK model (simbiology, pbpk, tce)

image thumbnail

updated 2 years ago

Using SimBiology for Mechanism-Based PK/PD Modeling in Preclinical & Discovery by Asawari Samant

Examples used in the March 2012 webinar: Using SimBiology for Mechanism-Based PK/PD Modeling (simbiology, pkpd, antibacterial)

antibioticDoseResponseGUI.m

doseResponse(mObj, drugName, strainName, PKPD, MIC)

doseResponsePlot(X1, Y1)

image thumbnail

updated almost 3 years ago

SimBiology model for PK/PD of anticancer drugs by Asawari Samant

SimBiology model describing the effect of anticancer drugs on tumor growth kinetics (simbiology, pkpd, tumor growth kinetics)

image thumbnail

updated almost 3 years ago

SimBiology model for PK/PD of antibacterial drugs by Asawari Samant

SimBiology model for PK/PD of antibacterial drugs (simbiology, pkpd, antibacterial drug)

Contact us