Systems Biology [MIT OpenCourseware]

http://ocw.mit.edu/OcwWeb/Physics/8-591JFall2004/CourseHome/index.htm

First submitted by Classroom Resources Team on 22 Jul 2008

Updated by Classroom Resources Team on 19 Jun 2009

Overview of modeling techniques in molecular and developmental biology and genetics (uses MATLAB)

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Date	Contributor	Description	Rating
19 Jun 2009	Classroom Resources Team	This course introduces the mathematical modeling techniques needed to address key questions in modern biology. An overview of modeling techniques in molecular biology and genetics, cell biology and developmental biology is covered. Key experiments that validate mathematical models are also discussed, as well as molecular, cellular, and developmental systems biology, bacterial chemotaxis, genetic oscillators, control theory and genetic networks, and gradient sensing systems. Additional specific topics include: constructing and modeling of genetic networks, lambda phage as a genetic switch, synthetic genetic switches, circadian rhythms, reaction diffusion equations, local activation and global inhibition models, center finding networks, general pattern formation models, modeling cell-cell communication, quorum sensing, and finally, models for Drosophila development. Course material created by Professor Alexander van Oudenaarden. Target audience: Graduate Institution: Massachusetts Institute of Technology Materials available: Problem sets or projects, Course outline or syllabus, Textbook recommendations, Downloadable code or data files Products: MATLAB

19 Jun 2009

Classroom Resources Team

This course introduces the mathematical modeling techniques needed to address key questions in modern biology. An overview of modeling techniques in molecular biology and genetics, cell biology and developmental biology is covered. Key experiments that validate mathematical models are also discussed, as well as molecular, cellular, and developmental systems biology, bacterial chemotaxis, genetic oscillators, control theory and genetic networks, and gradient sensing systems. Additional specific topics include: constructing and modeling of genetic networks, lambda phage as a genetic switch, synthetic genetic switches, circadian rhythms, reaction diffusion equations, local activation and global inhibition models, center finding networks, general pattern formation models, modeling cell-cell communication, quorum sensing, and finally, models for Drosophila development.
Course material created by Professor Alexander van Oudenaarden.

Target audience: Graduate

Institution: Massachusetts Institute of Technology

Materials available: Problem sets or projects, Course outline or syllabus, Textbook recommendations, Downloadable code or data files

Products: MATLAB

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Tag Activity

Tag	Applied By	Date/Time
language english	Classroom Resources Team	24 Nov 2009 at 11:11am
resource	Classroom Resources Team	24 Nov 2009 at 11:11am
academic	Classroom Resources Team	24 Nov 2009 at 11:11am
course materials	Classroom Resources Team	24 Nov 2009 at 11:11am
downloadable code	Classroom Resources Team	24 Nov 2009 at 11:11am
biological and health sciences	Classroom Resources Team	24 Nov 2009 at 11:11am
computational biology	Classroom Resources Team	24 Nov 2009 at 11:11am

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