This 2007 American Society of Engineering Education (ASEE) paper describes the motivation and process for the successful integration of MATLAB throughout the Chemical Engineering curriculum at Michigan State University. Students learn how to use MATLAB in a freshman-level course and then continue to use it extensively in as much as one course per semester during each of their remaining 3 years. This planned usage avoids the 2nd/3rd year gap in the application of MATLAB observed at many universities. Due to this systemic curricular change, MATLAB has become ingrained in the culture of the Chemical Engineering students and is recognized as the “go-to” tool; students actively choose to use it even when not specifically directed. Moreover, the students’ knowledge of MATLAB enables faculty to spend more time teaching engineering concepts and less time on mathematical manipulations. Furthermore, faculty are free to tackle richer, more complicated problems in their course. As a result, students gain a deeper understanding of the fundamental Chemical Engineering concepts.