SimBiology tutorial for PK/PD modeling: model building, simulation, and parameter estimation
|22 Apr 2014||MathWorks Classroom Resources Team||
In this tutorial, we will teach major concepts in SimBiology using simple examples of pharmacokinetic (PK) and simultaneous pharmacokinetic/pharmacodynamic (PK/PD) analyses. The example will begin with importing a PK dataset from a single subject, single oral dose study. After some basic preprocessing and visualization, we will fit the data to a one compartmental PK model with first-order dosing and linear elimination.