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From: "Justin " <justin.bourke@med.monash.edu.au>
Newsgroups: comp.soft-sys.matlab
Subject: Re: Guide errors creating a simple gui
Date: Mon, 10 Nov 2008 23:54:01 +0000 (UTC)
Organization: Monash Univ
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This bug was fixed in 2008b, but had a work around for earlier versions, not sure that it is what you are looking for, but it seems like it could help:

'System error resulting in a corrupted FIG-file when building a GUI in GUIDE' http://www.mathworks.com/support/bugreports/details.html?rp=452282