Am Mittwoch, 14. März 2012 08:10:14 UTC+1 schrieb smith :
> I need to calculate the bacterial specific growth rate for a batch process i.e I want to calculate the maximum growth rate at exponential growing condition. I have to calculate for a large set of varied cases.
> In the plot of log of biomass versus time,I have been taking the mean of slopes at each point (x2x1)/(t2t1) from time t=0 to the end of exponential growth phase. This method is not accurate,gives a reduced growth rate. For each case one has to take the mean of the slopes those are at higher range and exclude the lower values of slope.
> Is there any other way to get this?
If (t1,y1),...,(tn,yn) are your measurements of biomass versus time,
build an (nx2)matrix A with rows [1 ti] (1<=i<=n) and an (nx1)vector
b = [log(y1);log(y2);...;log(yn)].
If you now let
sol=A\b,
sol(2) gives you the fitted specific growth rate of the underlying
process.
Best wishes
Torsten.
