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        <listOfProducts>
          <speciesReference species="mw084b0a5a_f99e_4366_a441_daa1b9aa16a5"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <ci> mwd95c7aeb_9d7e_48f8_a317_bc84b7a58205 </ci>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="mwa6fe7490_4952_4ecb_9b7d_a37ce5e6ba4e" name="Corticosterone Binding" fast="false">
        <listOfReactants>
          <speciesReference species="mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e"/>
          <speciesReference species="mw084b0a5a_f99e_4366_a441_daa1b9aa16a5"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw47cd6dab_1caf_49c4_b08a_04d447b59c1d"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mw309abf84_768a_498b_9548_e4a923e7527b </ci>
                <ci> mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e </ci>
                <ci> mw084b0a5a_f99e_4366_a441_daa1b9aa16a5 </ci>
              </apply>
              <apply>
                <times/>
                <ci> mwd631f168_3be9_48df_aaaa_c2773a6aa1ad </ci>
                <ci> mw47cd6dab_1caf_49c4_b08a_04d447b59c1d </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw309abf84_768a_498b_9548_e4a923e7527b" name="kon_E" value="40000" units="MWDERIVEDUNIT_1__microgram__liter__hour"/>
            <parameter id="mwd631f168_3be9_48df_aaaa_c2773a6aa1ad" name="koff_E" value="1000" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mwf8cc3a3b_eae8_4ef0_b49e_c4e0a8048ec4" name="Other_Tissue Distribution" fast="false">
        <listOfReactants>
          <speciesReference species="mw56245930_bcf1_4a3c_b7f1_397b53aedce5"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mwd4bf68b2_5925_4963_95ef_b5aebca780e1"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mw24cfe22e_3fd3_4cc1_9a72_fb54fea5d039 </ci>
                <ci> mw56245930_bcf1_4a3c_b7f1_397b53aedce5 </ci>
              </apply>
              <apply>
                <times/>
                <ci> mw1fefc741_1b7e_44fa_8b79_dc01b6cb6d87 </ci>
                <ci> mwd4bf68b2_5925_4963_95ef_b5aebca780e1 </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw24cfe22e_3fd3_4cc1_9a72_fb54fea5d039" name="kiot" value="6.115" units="MWDERIVEDUNIT_1__hour"/>
            <parameter id="mw1fefc741_1b7e_44fa_8b79_dc01b6cb6d87" name="koti" value="5" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mwef1693c0_25bf_4f1b_b470_99207cffcf0d" name="Ald. Tissue Distribution" fast="false">
        <listOfReactants>
          <speciesReference species="mw44352f99_076d_49eb_a350_3b65e485ff05"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mwd6829ac0_b059_42b9_b651_97544f570108"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mwa6efbf46_6829_4148_ba55_e0d0938faad7 </ci>
                <ci> mw44352f99_076d_49eb_a350_3b65e485ff05 </ci>
              </apply>
              <apply>
                <times/>
                <ci> mw64b85612_cdf9_41bd_a9fa_382260daad5d </ci>
                <ci> mwd6829ac0_b059_42b9_b651_97544f570108 </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mwa6efbf46_6829_4148_ba55_e0d0938faad7" name="kti_ald" value="8406.25" units="MWDERIVEDUNIT_1__hour"/>
            <parameter id="mw64b85612_cdf9_41bd_a9fa_382260daad5d" name="kit_ald" value="5" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mw6de7d722_d218_4ec4_885b_359a407a998c" name="Ald. Fluid Distribution" fast="false">
        <listOfReactants>
          <speciesReference species="mwd6829ac0_b059_42b9_b651_97544f570108"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw888c7981_9426_4fe9_b5b3_0d1f85dfdd98"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mwf918b738_72ed_415c_8204_d7b7eb161fb7 </ci>
                <ci> mwd6829ac0_b059_42b9_b651_97544f570108 </ci>
              </apply>
              <apply>
                <times/>
                <ci> mw439d9d0e_c0f0_4fb2_b0b5_894b9bec5321 </ci>
                <ci> mw888c7981_9426_4fe9_b5b3_0d1f85dfdd98 </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mwf918b738_72ed_415c_8204_d7b7eb161fb7" name="kip_ald" value="500" units="MWDERIVEDUNIT_1__hour"/>
            <parameter id="mw439d9d0e_c0f0_4fb2_b0b5_894b9bec5321" name="kpi_ald" value="2242" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mw6a7d4e7e_0e0e_4f96_96fa_1ce2a7839077" name="Ald. OT Distribution" fast="false">
        <listOfReactants>
          <speciesReference species="mwd6829ac0_b059_42b9_b651_97544f570108"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw4e9c92e0_7dc0_4ccd_bc28_c9ca41ff8fc8"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mw36839b4a_f74d_4cbb_9beb_a5cee7dd5058 </ci>
                <ci> mwd6829ac0_b059_42b9_b651_97544f570108 </ci>
              </apply>
              <apply>
                <times/>
                <ci> mw14109f4e_6be4_4550_8b39_1b74c7ed8b2b </ci>
                <ci> mw4e9c92e0_7dc0_4ccd_bc28_c9ca41ff8fc8 </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw36839b4a_f74d_4cbb_9beb_a5cee7dd5058" name="kiot_ald" value="6.115" units="MWDERIVEDUNIT_1__hour"/>
            <parameter id="mw14109f4e_6be4_4550_8b39_1b74c7ed8b2b" name="koti_ald" value="5" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mw790c2e71_f675_463b_8162_88bcf6068604" name="Aldosterone Elimination" reversible="false" fast="false">
        <listOfReactants>
          <speciesReference species="mw888c7981_9426_4fe9_b5b3_0d1f85dfdd98"/>
        </listOfReactants>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> mw5b64ea81_3e6b_4e16_be1f_a70fd932b751 </ci>
              <ci> mw888c7981_9426_4fe9_b5b3_0d1f85dfdd98 </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw5b64ea81_3e6b_4e16_be1f_a70fd932b751" name="kel_ald" value="16" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mwa0624629_71b4_4459_9e51_e1a645f77eb2" name="Corticosterone Synthesis" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <ci> mw5488b7a1_2bc9_447c_9daf_fb02fae8e471 </ci>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="mwca81e3eb_55c0_4443_a2b1_559407feb5df" name="Aldosterone_Synthesis" reversible="false" fast="false">
        <listOfReactants>
          <speciesReference species="mw47cd6dab_1caf_49c4_b08a_04d447b59c1d"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw084b0a5a_f99e_4366_a441_daa1b9aa16a5"/>
          <speciesReference species="mw44352f99_076d_49eb_a350_3b65e485ff05"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> mw84e7c784_4c7f_4c47_b744_e67c3dbf0de8 </ci>
              <ci> mw47cd6dab_1caf_49c4_b08a_04d447b59c1d </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw84e7c784_4c7f_4c47_b744_e67c3dbf0de8" name="kcat_E" value="40" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mwe5545474_7e68_49ea_9788_a9039f9543aa" name="Corticosterone Elimination" reversible="false" fast="false">
        <listOfReactants>
          <speciesReference species="mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e"/>
        </listOfReactants>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> mw58c746f2_b695_4776_9b52_048e7fc65aff </ci>
              <ci> mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e </ci>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="mwdf6031be_4120_43a1_a08d_e8f19ba6d6f9" name="ES Deg" reversible="false" fast="false">
        <listOfReactants>
          <speciesReference species="mw47cd6dab_1caf_49c4_b08a_04d447b59c1d"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> mwdfb8cb26_a87a_40b6_981a_8b2884f08fe4 </ci>
              <ci> mw47cd6dab_1caf_49c4_b08a_04d447b59c1d </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mwdfb8cb26_a87a_40b6_981a_8b2884f08fe4" name="kdeg_ES" value="0.2" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mw074cbdb1_38bd_4795_8ed7_785a1f104df8" name="ES Binding" fast="false">
        <listOfReactants>
          <speciesReference species="mw51ecfe17_61ab_4835_8f9c_0de2eb454d0f"/>
          <speciesReference species="mw47cd6dab_1caf_49c4_b08a_04d447b59c1d"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw70a5b399_743e_4478_83ea_d2261bc75853"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mw938960f6_ca57_483f_a316_49f9f10786b2 </ci>
                <ci> mw51ecfe17_61ab_4835_8f9c_0de2eb454d0f </ci>
                <ci> mw47cd6dab_1caf_49c4_b08a_04d447b59c1d </ci>
              </apply>
              <apply>
                <times/>
                <ci> mw7d7402cd_bb5b_4a33_ab7f_fcfbd62a94f0 </ci>
                <ci> mw70a5b399_743e_4478_83ea_d2261bc75853 </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw938960f6_ca57_483f_a316_49f9f10786b2" name="kon_ES" value="0.1" units="MWDERIVEDUNIT_1__microgram__liter__hour"/>
            <parameter id="mw7d7402cd_bb5b_4a33_ab7f_fcfbd62a94f0" name="koff_ES" value="0.1" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mw3136b3d5_8164_4599_9cd8_5cfe0549daaa" name="ESI Binding" fast="false">
        <listOfReactants>
          <speciesReference species="mwf21cdb04_7a55_4846_9514_8cdcdccc99a9"/>
          <speciesReference species="mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw70a5b399_743e_4478_83ea_d2261bc75853"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <minus/>
              <apply>
                <times/>
                <ci> mw362618cf_670c_46ad_a1f8_f8c9285554f1 </ci>
                <ci> mwf21cdb04_7a55_4846_9514_8cdcdccc99a9 </ci>
                <ci> mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e </ci>
              </apply>
              <apply>
                <times/>
                <ci> mwd5898a40_4fc9_44fa_998f_520d7d44ff95 </ci>
                <ci> mw70a5b399_743e_4478_83ea_d2261bc75853 </ci>
              </apply>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mw362618cf_670c_46ad_a1f8_f8c9285554f1" name="kon_ESI" value="40000" units="MWDERIVEDUNIT_1__microgram__liter__hour"/>
            <parameter id="mwd5898a40_4fc9_44fa_998f_520d7d44ff95" name="koff_ESI" value="1000" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
      <reaction id="mw4824ff04_04a8_41e9_88da_46b516bdd695" name="ESI Deg" reversible="false" fast="false">
        <listOfReactants>
          <speciesReference species="mw70a5b399_743e_4478_83ea_d2261bc75853"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="mw51ecfe17_61ab_4835_8f9c_0de2eb454d0f"/>
          <speciesReference species="mwe04f6eeb_8873_4bd6_98a5_45ba1b254e7e"/>
        </listOfProducts>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <ci> mwbfae98c3_28d5_4c1f_ac56_fea9aa4ca7ee </ci>
              <ci> mw70a5b399_743e_4478_83ea_d2261bc75853 </ci>
            </apply>
          </math>
          <listOfParameters>
            <parameter id="mwbfae98c3_28d5_4c1f_ac56_fea9aa4ca7ee" name="kdeg_ESI" value="0.2" units="MWDERIVEDUNIT_1__hour"/>
          </listOfParameters>
        </kineticLaw>
      </reaction>
    </listOfReactions>
  </model>
</sbml>
