<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level2/version4" level="2" version="4">
  <annotation>
    <SimBiology xmlns="http://www.mathworks.com">
      <Version Major="5" Minor="3" Point="0"/>
    </SimBiology>
  </annotation>
  <model id="Holzhutter2004_Erythrocyte_Metabolism" name="Erythrocyte_Metabolism">
    <notes>
      <body xmlns="http://www.w3.org/1999/xhtml">
        <notes>
          <body xmlns="http://www.w3.org/1999/xhtml">
            <p align="right">
              <font color="#FFFFFF">.</font>
            </p>
            <p align="right">
              <font color="#FFFFFF">.</font>
            </p>
            <p align="right">
              <font color="#FFFFFF">.</font>
            </p>
            <p align="left">
              <font face="Arial, Helvetica, sans-serif">
                <b>
                  <a href="http://www.sbml.org/">SBML</a>
              level 2 code generated for the JWS Online project by Jacky Snoep using          <a href="http://pysces.sourceforge.net/">PySCeS</a>
                  <br/>
              Run this model online at          <a href="http://jjj.biochem.sun.ac.za/">http://jjj.biochem.sun.ac.za</a>
                  <br/>
              To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004)          <a href="http://bioinformatics.oupjournals.org/cgi/content/abstract/20/13/2143">Web-based 
modelling using JWS Online</a>
              , Bioinformatics, 20:2143-2144          </b>
                </font>
              </p>
              <p align="right">
                <font color="#FFFFFF">.</font>
              </p>
              <p align="right">
                <font color="#FFFFFF">.</font>
              </p>
              <p align="right">
                <font color="#FFFFFF">.</font>
              </p>
              <p align="right">
                <font color="#FFFFFF">.</font>
              </p>
              <p align="right">
                <font color="#FFFFFF">.</font>
              </p>
              <p align="right">
                <font color="#FFFFFF">.</font>
              </p>
              <p>
                <u>Biomodels Curation</u>
          The model simulates the flux values as given for &quot;kinetic model&quot; in Table 1 of the paper. The model was successfully tested on Jarnac.      </p>
              </body>
            </notes>
          </body>
        </notes>
        <listOfUnitDefinitions>
          <unitDefinition id="MWUSERUNIT_mM" name="mM">
            <listOfUnits>
              <unit kind="metre" exponent="-3"/>
              <unit kind="mole"/>
              <unit kind="dimensionless" multiplier="1"/>
            </listOfUnits>
          </unitDefinition>
          <unitDefinition id="MWUSERUNIT_mM_per_hour" name="mM_per_hour">
            <listOfUnits>
              <unit kind="mole"/>
              <unit kind="second" exponent="-1"/>
              <unit kind="dimensionless" multiplier="2.77777777777778e-07"/>
            </listOfUnits>
          </unitDefinition>
          <unitDefinition id="MWDERIVEDUNIT_1__hour" name="1/hour">
            <listOfUnits>
              <unit kind="second" exponent="-1"/>
              <unit kind="dimensionless" multiplier="0.000277777777777778"/>
            </listOfUnits>
          </unitDefinition>
          <unitDefinition id="MWUSERUNIT_per_mM_hour" name="per_mM_hour">
            <listOfUnits>
              <unit kind="mole" exponent="-1"/>
              <unit kind="second" exponent="-1"/>
              <unit kind="dimensionless" multiplier="0.277777777777778"/>
            </listOfUnits>
          </unitDefinition>
          <unitDefinition id="MWUSERUNIT_hour_inverse" name="hour_inverse">
            <listOfUnits>
              <unit kind="mole"/>
              <unit kind="second" exponent="-1"/>
              <unit kind="dimensionless"/>
            </listOfUnits>
          </unitDefinition>
        </listOfUnitDefinitions>
        <listOfCompartments>
          <compartment id="mw21d4d476_8151_49e5_8afc_b187ec173e51" name="red_cell" size="1"/>
          <compartment id="mwe6c873af_a8c2_44e0_86ad_94c0cb22d5de" name="plasma" size="1"/>
        </listOfCompartments>
        <listOfSpecies>
          <species id="Glcin" name="Glucose" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="4.5663"/>
          <species id="MgATP" name="MgATP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="1.4"/>
          <species id="Glc6P" name="Glucose 6-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0394"/>
          <species id="MgADP" name="MgADP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.1"/>
          <species id="Fru6P" name="Fructose 6-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0153"/>
          <species id="Fru16P2" name="Fructose 1,6-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0097"/>
          <species id="GraP" name="Glyceraldehyde 3-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0061"/>
          <species id="DHAP" name="Dihydroxyacetone phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.1492"/>
          <species id="Phi" name="Phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.9992"/>
          <species id="NAD" name="NAD" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0653"/>
          <species id="Gri13P2" name="1,3-Bisphospho-D-glycerate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0005"/>
          <species id="NADH" name="NADH" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0002"/>
          <species id="Gri3P" name="3-Phospho-D-glycerate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0658"/>
          <species id="Gri23P2f" name="2,3-Bisphospho-D-glycerate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="2.0601"/>
          <species id="Gri2P" name="2-Phospho-D-glycerate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0084"/>
          <species id="PEP" name="Phosphoenolpyruvate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0109"/>
          <species id="Pyr" name="Pyruvate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.084"/>
          <species id="Lac" name="Lactate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="1.6803"/>
          <species id="NADPHf" name="NADPH" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.004"/>
          <species id="NADPf" name="NADP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="AMPf" name="AMP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="ADPf" name="ADP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.25"/>
          <species id="GlcA6P" name="Phospho-D-glucono-1,5-lactone" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.025"/>
          <species id="Rul5P" name="Ribulose 5-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0047"/>
          <species id="GSSG" name="Oxidized Glutathione" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0004"/>
          <species id="GSH" name="Reduced Glutathione" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="3.1136"/>
          <species id="Xul5P" name="Xylulose 5-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0127"/>
          <species id="Rib5P" name="Ribose 5-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.014"/>
          <species id="Sed7P" name="Sedoheptulose 7-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0154"/>
          <species id="E4P" name="Erythrose 4-phosphate" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.0063"/>
          <species id="MgAMP" name="MgAMP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="ATPf" name="ATP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.25"/>
          <species id="Mgf" name="Mg" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.8"/>
          <species id="MgGri23P2" name="MgGri23P2" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.5"/>
          <species id="P1NADP" name="Protein1 bound NADP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="P1f" name="Protein1" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="P1NADPH" name="Protein1 bound NADPH" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.024"/>
          <species id="P2NADP" name="Protein2 bound NADP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="P2f" name="Protein2" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0"/>
          <species id="P2NADPH" name="Protein2 bound NADPH" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.024"/>
          <species id="PRPP" name="PRPP" compartment="mw21d4d476_8151_49e5_8afc_b187ec173e51" initialAmount="0.01"/>
          <species id="mw7466adf7_85fd_472f_bf01_8f68b970cb4f" name="Plasma Glucose" compartment="mwe6c873af_a8c2_44e0_86ad_94c0cb22d5de" initialAmount="5" boundaryCondition="true"/>
          <species id="mw3f64eb09_4a72_4b60_b7f2_68a118caaf7a" name="Plasma Pyruvate" compartment="mwe6c873af_a8c2_44e0_86ad_94c0cb22d5de" initialAmount="0.084" boundaryCondition="true"/>
          <species id="mwfe0bb4bb_890b_44f4_af0c_a3168bb257e9" name="Plasma Phosphate" compartment="mwe6c873af_a8c2_44e0_86ad_94c0cb22d5de" initialAmount="1" boundaryCondition="true"/>
          <species id="mw8c5690e1_b876_4c4d_bc4e_d34e76b52173" name="Plasma Lactate" compartment="mwe6c873af_a8c2_44e0_86ad_94c0cb22d5de" initialAmount="1.68" boundaryCondition="true"/>
        </listOfSpecies>
        <listOfReactions>
          <reaction id="vHEX" name="Hexokinase" fast="false">
            <listOfReactants>
              <speciesReference species="Glcin"/>
              <speciesReference species="MgATP"/>
              <speciesReference species="Mgf"/>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Glc6P"/>
              <speciesReference species="MgADP"/>
              <speciesReference species="Mgf"/>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> Inhibv1 </ci>
                          <ci> Glcin </ci>
                        </apply>
                        <apply>
                          <plus/>
                          <ci> Glcin </ci>
                          <ci> KMGlcv1 </ci>
                        </apply>
                      </apply>
                      <apply>
                        <divide/>
                        <ci> Vmax1v1 </ci>
                        <ci> KMgATPv1 </ci>
                      </apply>
                      <apply>
                        <minus/>
                        <apply>
                          <plus/>
                          <ci> MgATP </ci>
                          <apply>
                            <divide/>
                            <apply>
                              <times/>
                              <apply>
                                <divide/>
                                <ci> Vmax2v1 </ci>
                                <ci> Vmax1v1 </ci>
                              </apply>
                              <ci> MgATP </ci>
                              <ci> Mgf </ci>
                            </apply>
                            <ci> KMgATPMgv1 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> Glc6P </ci>
                            <ci> MgADP </ci>
                          </apply>
                          <ci> Keqv1 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <cn type="integer"> 1 </cn>
                      <apply>
                        <times/>
                        <apply>
                          <divide/>
                          <ci> MgATP </ci>
                          <ci> KMgATPv1 </ci>
                        </apply>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> Mgf </ci>
                            <ci> KMgATPMgv1 </ci>
                          </apply>
                        </apply>
                      </apply>
                      <apply>
                        <divide/>
                        <ci> Mgf </ci>
                        <ci> KMgv1 </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <cn> 1.55 </cn>
                          <apply>
                            <divide/>
                            <ci> Glc6P </ci>
                            <ci> KGlc6Pv1 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> Mgf </ci>
                            <ci> KMgv1 </ci>
                          </apply>
                        </apply>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <plus/>
                          <ci> Gri23P2f </ci>
                          <ci> MgGri23P2 </ci>
                        </apply>
                        <ci> K23P2Gv1 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> Mgf </ci>
                          <apply>
                            <plus/>
                            <ci> Gri23P2f </ci>
                            <ci> MgGri23P2 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <times/>
                          <ci> KMgv1 </ci>
                          <ci> KMg23P2Gv1 </ci>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Inhibv1" name="Inhibv1" value="1" units="dimensionless"/>
                <parameter id="KMGlcv1" name="KMGlcv1" value="0.1" units="MWUSERUNIT_mM"/>
                <parameter id="Vmax1v1" name="Vmax1v1" value="15.8" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KMgATPv1" name="KMgATPv1" value="1.44" units="MWUSERUNIT_mM"/>
                <parameter id="Vmax2v1" name="Vmax2v1" value="33.2" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KMgATPMgv1" name="KMgATPMgv1" value="1.14" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv1" name="Keqv1" value="3900" units="MWUSERUNIT_mM"/>
                <parameter id="KMgv1" name="KMgv1" value="1.03" units="MWUSERUNIT_mM"/>
                <parameter id="KGlc6Pv1" name="KGlc6Pv1" value="0.0045" units="MWUSERUNIT_mM"/>
                <parameter id="K23P2Gv1" name="K23P2Gv1" value="2.7" units="MWUSERUNIT_mM"/>
                <parameter id="KMg23P2Gv1" name="KMg23P2Gv1" value="3.44" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vGPI" name="Glucosephosphate isomerase" fast="false">
            <listOfReactants>
              <speciesReference species="Glc6P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Fru6P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv2 </ci>
                      <apply>
                        <minus/>
                        <ci> Glc6P </ci>
                        <apply>
                          <divide/>
                          <ci> Fru6P </ci>
                          <ci> Keqv2 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> Glc6P </ci>
                      <apply>
                        <times/>
                        <ci> KGlc6Pv2 </ci>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> Fru6P </ci>
                            <ci> KFru6Pv2 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv2" name="Vmaxv2" value="935" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv2" name="Keqv2" value="0.3925" units="dimensionless"/>
                <parameter id="KGlc6Pv2" name="KGlc6Pv2" value="0.182" units="MWUSERUNIT_mM"/>
                <parameter id="KFru6Pv2" name="KFru6Pv2" value="0.071" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPFK" name="Phosphofructokinase" fast="false">
            <listOfReactants>
              <speciesReference species="MgATP"/>
              <speciesReference species="Fru6P"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="Mgf"/>
              <speciesReference species="AMPf"/>
              <speciesReference species="MgAMP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Fru16P2"/>
              <speciesReference species="MgADP"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="Mgf"/>
              <speciesReference species="AMPf"/>
              <speciesReference species="MgAMP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv3 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> Fru6P </ci>
                          <ci> MgATP </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> Fru16P2 </ci>
                            <ci> MgADP </ci>
                          </apply>
                          <ci> Keqv3 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <plus/>
                        <ci> Fru6P </ci>
                        <ci> KFru6Pv3 </ci>
                      </apply>
                      <apply>
                        <plus/>
                        <ci> MgATP </ci>
                        <ci> KMgATPv3 </ci>
                      </apply>
                      <apply>
                        <plus/>
                        <cn type="integer"> 1 </cn>
                        <apply>
                          <times/>
                          <ci> L0v3 </ci>
                          <apply>
                            <power/>
                            <apply>
                              <divide/>
                              <apply>
                                <times/>
                                <apply>
                                  <plus/>
                                  <cn type="integer"> 1 </cn>
                                  <apply>
                                    <divide/>
                                    <ci> ATPf </ci>
                                    <ci> KATPv3 </ci>
                                  </apply>
                                </apply>
                                <apply>
                                  <plus/>
                                  <cn type="integer"> 1 </cn>
                                  <apply>
                                    <divide/>
                                    <ci> Mgf </ci>
                                    <ci> KMgv3 </ci>
                                  </apply>
                                </apply>
                              </apply>
                              <apply>
                                <times/>
                                <apply>
                                  <plus/>
                                  <cn type="integer"> 1 </cn>
                                  <apply>
                                    <divide/>
                                    <apply>
                                      <plus/>
                                      <ci> AMPf </ci>
                                      <ci> MgAMP </ci>
                                    </apply>
                                    <ci> KAMPv3 </ci>
                                  </apply>
                                </apply>
                                <apply>
                                  <plus/>
                                  <cn type="integer"> 1 </cn>
                                  <apply>
                                    <divide/>
                                    <ci> Fru6P </ci>
                                    <ci> KFru6Pv3 </ci>
                                  </apply>
                                </apply>
                              </apply>
                            </apply>
                            <cn type="integer"> 4 </cn>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv3" name="Vmaxv3" value="239" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv3" name="Keqv3" value="100000" units="dimensionless"/>
                <parameter id="KFru6Pv3" name="KFru6Pv3" value="0.1" units="MWUSERUNIT_mM"/>
                <parameter id="KMgATPv3" name="KMgATPv3" value="0.068" units="MWUSERUNIT_mM"/>
                <parameter id="L0v3" name="L0v3" value="0.001072" units="dimensionless"/>
                <parameter id="KATPv3" name="KATPv3" value="0.01" units="MWUSERUNIT_mM"/>
                <parameter id="KMgv3" name="KMgv3" value="0.44" units="MWUSERUNIT_mM"/>
                <parameter id="KAMPv3" name="KAMPv3" value="0.033" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vALD" name="Aldolase" fast="false">
            <listOfReactants>
              <speciesReference species="Fru16P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GraP"/>
              <speciesReference species="DHAP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> Vmaxv4 </ci>
                        <ci> KFru16P2v4 </ci>
                      </apply>
                      <apply>
                        <minus/>
                        <ci> Fru16P2 </ci>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> GraP </ci>
                            <ci> DHAP </ci>
                          </apply>
                          <ci> Keqv4 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <cn type="integer"> 1 </cn>
                      <apply>
                        <divide/>
                        <ci> Fru16P2 </ci>
                        <ci> KFru16P2v4 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <ci> GraP </ci>
                        <ci> KiGraPv4 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> DHAP </ci>
                          <apply>
                            <plus/>
                            <ci> GraP </ci>
                            <ci> KGraPv4 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <times/>
                          <ci> KDHAPv4 </ci>
                          <ci> KiGraPv4 </ci>
                        </apply>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> Fru16P2 </ci>
                          <ci> GraP </ci>
                        </apply>
                        <apply>
                          <times/>
                          <ci> KFru16P2v4 </ci>
                          <ci> KiiGraPv4 </ci>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv4" name="Vmaxv4" value="98.91000366" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KFru16P2v4" name="KFru16P2v4" value="0.0071" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv4" name="Keqv4" value="0.114" units="MWUSERUNIT_mM"/>
                <parameter id="KiGraPv4" name="KiGraPv4" value="0.0572" units="MWUSERUNIT_mM"/>
                <parameter id="KGraPv4" name="KGraPv4" value="0.1906" units="MWUSERUNIT_mM"/>
                <parameter id="KDHAPv4" name="KDHAPv4" value="0.0364" units="MWUSERUNIT_mM"/>
                <parameter id="KiiGraPv4" name="KiiGraPv4" value="0.176" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vTPI" name="Triosephosphate isomerase" fast="false">
            <listOfReactants>
              <speciesReference species="DHAP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GraP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv5 </ci>
                      <apply>
                        <minus/>
                        <ci> DHAP </ci>
                        <apply>
                          <divide/>
                          <ci> GraP </ci>
                          <ci> Keqv5 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> DHAP </ci>
                      <apply>
                        <times/>
                        <ci> KDHAPv5 </ci>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> GraP </ci>
                            <ci> KGraPv5 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv5" name="Vmaxv5" value="5456.600098" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv5" name="Keqv5" value="0.0407" units="dimensionless"/>
                <parameter id="KDHAPv5" name="KDHAPv5" value="0.838" units="MWUSERUNIT_mM"/>
                <parameter id="KGraPv5" name="KGraPv5" value="0.428" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vGAPDH" name="Glyceraldehyde 3-phosphate dehydrogenase" fast="false">
            <listOfReactants>
              <speciesReference species="GraP"/>
              <speciesReference species="Phi"/>
              <speciesReference species="NAD"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="NADH"/>
              <speciesReference species="Gri13P2"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> Vmaxv6 </ci>
                        <apply>
                          <times/>
                          <ci> KNADv6 </ci>
                          <ci> KGraPv6 </ci>
                          <ci> KPv6 </ci>
                        </apply>
                      </apply>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> NAD </ci>
                          <ci> GraP </ci>
                          <ci> Phi </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> Gri13P2 </ci>
                            <ci> NADH </ci>
                          </apply>
                          <ci> Keqv6 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <minus/>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> NAD </ci>
                              <ci> KNADv6 </ci>
                            </apply>
                          </apply>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> GraP </ci>
                              <ci> KGraPv6 </ci>
                            </apply>
                          </apply>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> Phi </ci>
                              <ci> KPv6 </ci>
                            </apply>
                          </apply>
                        </apply>
                        <apply>
                          <times/>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> NADH </ci>
                              <ci> KNADHv6 </ci>
                            </apply>
                          </apply>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> Gri13P2 </ci>
                              <ci> K13P2Gv6 </ci>
                            </apply>
                          </apply>
                        </apply>
                      </apply>
                      <cn type="integer"> 1 </cn>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv6" name="Vmaxv6" value="4300" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KNADv6" name="KNADv6" value="0.05" units="MWUSERUNIT_mM"/>
                <parameter id="KGraPv6" name="KGraPv6" value="0.005" units="MWUSERUNIT_mM"/>
                <parameter id="KPv6" name="KPv6" value="3.9" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv6" name="Keqv6" value="0.000192" units="dimensionless"/>
                <parameter id="KNADHv6" name="KNADHv6" value="0.0083" units="MWUSERUNIT_mM"/>
                <parameter id="K13P2Gv6" name="K13P2Gv6" value="0.0035" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPGK" name="Phosphoglycerate kinase" fast="false">
            <listOfReactants>
              <speciesReference species="MgADP"/>
              <speciesReference species="Gri13P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="MgATP"/>
              <speciesReference species="Gri3P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> Vmaxv7 </ci>
                        <apply>
                          <times/>
                          <ci> KMgADPv7 </ci>
                          <ci> K13P2Gv7 </ci>
                        </apply>
                      </apply>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> MgADP </ci>
                          <ci> Gri13P2 </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> MgATP </ci>
                            <ci> Gri3P </ci>
                          </apply>
                          <ci> Keqv7 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <minus/>
                      <apply>
                        <plus/>
                        <apply>
                          <times/>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> MgADP </ci>
                              <ci> KMgADPv7 </ci>
                            </apply>
                          </apply>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> Gri13P2 </ci>
                              <ci> K13P2Gv7 </ci>
                            </apply>
                          </apply>
                        </apply>
                        <apply>
                          <times/>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> MgATP </ci>
                              <ci> KMgATPv7 </ci>
                            </apply>
                          </apply>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> Gri3P </ci>
                              <ci> K3PGv7 </ci>
                            </apply>
                          </apply>
                        </apply>
                      </apply>
                      <cn type="integer"> 1 </cn>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv7" name="Vmaxv7" value="5000" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KMgADPv7" name="KMgADPv7" value="0.35" units="MWUSERUNIT_mM"/>
                <parameter id="K13P2Gv7" name="K13P2Gv7" value="0.002" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv7" name="Keqv7" value="1455" units="dimensionless"/>
                <parameter id="KMgATPv7" name="KMgATPv7" value="0.48" units="MWUSERUNIT_mM"/>
                <parameter id="K3PGv7" name="K3PGv7" value="1.2" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vBPGM" name="Bisphosphoglycerate mutase" fast="false">
            <listOfReactants>
              <speciesReference species="Gri13P2"/>
              <speciesReference species="MgGri23P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> kDPGMv8 </ci>
                      <apply>
                        <minus/>
                        <ci> Gri13P2 </ci>
                        <apply>
                          <divide/>
                          <apply>
                            <plus/>
                            <ci> Gri23P2f </ci>
                            <ci> MgGri23P2 </ci>
                          </apply>
                          <ci> Keqv8 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <cn type="integer"> 1 </cn>
                      <apply>
                        <divide/>
                        <apply>
                          <plus/>
                          <ci> Gri23P2f </ci>
                          <ci> MgGri23P2 </ci>
                        </apply>
                        <ci> K23P2Gv8 </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="kDPGMv8" name="kDPGMv8" value="76000" units="MWDERIVEDUNIT_1__hour"/>
                <parameter id="Keqv8" name="Keqv8" value="100000" units="dimensionless"/>
                <parameter id="K23P2Gv8" name="K23P2Gv8" value="0.04" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vBPGP" name="Bisphosphoglycerate phosphatase" fast="false">
            <listOfReactants>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Gri3P"/>
              <speciesReference species="Phi"/>
              <speciesReference species="MgGri23P2"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv9 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <plus/>
                          <ci> Gri23P2f </ci>
                          <ci> MgGri23P2 </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <ci> Gri3P </ci>
                          <ci> Keqv9 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> Gri23P2f </ci>
                      <ci> MgGri23P2 </ci>
                      <ci> K23P2Gv9 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv9" name="Vmaxv9" value="0.53" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv9" name="Keqv9" value="100000" units="dimensionless"/>
                <parameter id="K23P2Gv9" name="K23P2Gv9" value="0.2" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPGM" name="Phosphoglycerate mutase" fast="false">
            <listOfReactants>
              <speciesReference species="Gri3P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Gri2P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv10 </ci>
                      <apply>
                        <minus/>
                        <ci> Gri3P </ci>
                        <apply>
                          <divide/>
                          <ci> Gri2P </ci>
                          <ci> Keqv10 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> Gri3P </ci>
                      <apply>
                        <times/>
                        <ci> K3PGv10 </ci>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> Gri2P </ci>
                            <ci> K2PGv10 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv10" name="Vmaxv10" value="2000" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv10" name="Keqv10" value="0.145" units="dimensionless"/>
                <parameter id="K3PGv10" name="K3PGv10" value="5" units="MWUSERUNIT_mM"/>
                <parameter id="K2PGv10" name="K2PGv10" value="1" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vENO" name="Enolase" fast="false">
            <listOfReactants>
              <speciesReference species="Gri2P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="PEP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv11 </ci>
                      <apply>
                        <minus/>
                        <ci> Gri2P </ci>
                        <apply>
                          <divide/>
                          <ci> PEP </ci>
                          <ci> Keqv11 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> Gri2P </ci>
                      <apply>
                        <times/>
                        <ci> K2PGv11 </ci>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> PEP </ci>
                            <ci> KPEPv11 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv11" name="Vmaxv11" value="1500" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv11" name="Keqv11" value="1.7" units="dimensionless"/>
                <parameter id="K2PGv11" name="K2PGv11" value="1" units="MWUSERUNIT_mM"/>
                <parameter id="KPEPv11" name="KPEPv11" value="1" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPK" name="Pyruvate kinase" fast="false">
            <listOfReactants>
              <speciesReference species="PEP"/>
              <speciesReference species="MgADP"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="Fru16P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="MgATP"/>
              <speciesReference species="Pyr"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="Fru16P2"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv12 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> PEP </ci>
                          <ci> MgADP </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> Pyr </ci>
                            <ci> MgATP </ci>
                          </apply>
                          <ci> Keqv12 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <plus/>
                        <ci> PEP </ci>
                        <ci> KPEPv12 </ci>
                      </apply>
                      <apply>
                        <plus/>
                        <ci> MgADP </ci>
                        <ci> KMgADPv12 </ci>
                      </apply>
                      <apply>
                        <plus/>
                        <cn type="integer"> 1 </cn>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> L0v12 </ci>
                            <apply>
                              <power/>
                              <apply>
                                <plus/>
                                <cn type="integer"> 1 </cn>
                                <apply>
                                  <divide/>
                                  <apply>
                                    <plus/>
                                    <ci> ATPf </ci>
                                    <ci> MgATP </ci>
                                  </apply>
                                  <ci> KATPv12 </ci>
                                </apply>
                              </apply>
                              <cn type="integer"> 4 </cn>
                            </apply>
                          </apply>
                          <apply>
                            <times/>
                            <apply>
                              <power/>
                              <apply>
                                <plus/>
                                <cn type="integer"> 1 </cn>
                                <apply>
                                  <divide/>
                                  <ci> PEP </ci>
                                  <ci> KPEPv12 </ci>
                                </apply>
                              </apply>
                              <cn type="integer"> 4 </cn>
                            </apply>
                            <apply>
                              <power/>
                              <apply>
                                <plus/>
                                <cn type="integer"> 1 </cn>
                                <apply>
                                  <divide/>
                                  <ci> Fru16P2 </ci>
                                  <ci> KFru16P2v12 </ci>
                                </apply>
                              </apply>
                              <cn type="integer"> 4 </cn>
                            </apply>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv12" name="Vmaxv12" value="570" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv12" name="Keqv12" value="13790" units="dimensionless"/>
                <parameter id="KPEPv12" name="KPEPv12" value="0.225" units="MWUSERUNIT_mM"/>
                <parameter id="KMgADPv12" name="KMgADPv12" value="0.474" units="MWUSERUNIT_mM"/>
                <parameter id="L0v12" name="L0v12" value="19" units="dimensionless"/>
                <parameter id="KATPv12" name="KATPv12" value="3.39" units="MWUSERUNIT_mM"/>
                <parameter id="KFru16P2v12" name="KFru16P2v12" value="0.005" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vLDHNADH" name="Lactate dehydrogenase" fast="false">
            <listOfReactants>
              <speciesReference species="NADH"/>
              <speciesReference species="Pyr"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Lac"/>
              <speciesReference species="NAD"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> Vmaxv13 </ci>
                  <apply>
                    <minus/>
                    <apply>
                      <times/>
                      <ci> Pyr </ci>
                      <ci> NADH </ci>
                    </apply>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> Lac </ci>
                        <ci> NAD </ci>
                      </apply>
                      <ci> Keqv13 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv13" name="Vmaxv13" value="2800000" units="MWUSERUNIT_per_mM_hour"/>
                <parameter id="Keqv13" name="Keqv13" value="9090" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vLDHNADPH" name="Lactate dehydrogenase_1" fast="false">
            <listOfReactants>
              <speciesReference species="Pyr"/>
              <speciesReference species="NADPHf"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Lac"/>
              <speciesReference species="NADPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> kLDHv14 </ci>
                  <apply>
                    <minus/>
                    <apply>
                      <times/>
                      <ci> Pyr </ci>
                      <ci> NADPHf </ci>
                    </apply>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> Lac </ci>
                        <ci> NADPf </ci>
                      </apply>
                      <ci> Keqv14 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="kLDHv14" name="kLDHv14" value="243.4" units="MWUSERUNIT_per_mM_hour"/>
                <parameter id="Keqv14" name="Keqv14" value="14181.8" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vATPase" name="ATPase" fast="false">
            <listOfReactants>
              <speciesReference species="MgATP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Phi"/>
              <speciesReference species="MgADP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> kATPasev15 </ci>
                  <ci> MgATP </ci>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="kATPasev15" name="kATPasev15" value="1.68" units="MWUSERUNIT_hour_inverse"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vAK" name="Adenylate kinase" fast="false">
            <listOfReactants>
              <speciesReference species="MgATP"/>
              <speciesReference species="AMPf"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="ADPf"/>
              <speciesReference species="MgADP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> Vmaxv16 </ci>
                        <apply>
                          <times/>
                          <ci> KATPv16 </ci>
                          <ci> KAMPv16 </ci>
                        </apply>
                      </apply>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> MgATP </ci>
                          <ci> AMPf </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> MgADP </ci>
                            <ci> ADPf </ci>
                          </apply>
                          <ci> Keqv16 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> MgATP </ci>
                            <ci> KATPv16 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> AMPf </ci>
                            <ci> KAMPv16 </ci>
                          </apply>
                        </apply>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <plus/>
                          <ci> MgADP </ci>
                          <ci> ADPf </ci>
                        </apply>
                        <ci> KADPv16 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> MgADP </ci>
                          <ci> ADPf </ci>
                        </apply>
                        <apply>
                          <power/>
                          <ci> KADPv16 </ci>
                          <cn type="integer"> 2 </cn>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv16" name="Vmaxv16" value="1380" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KATPv16" name="KATPv16" value="0.09" units="MWUSERUNIT_mM"/>
                <parameter id="KAMPv16" name="KAMPv16" value="0.08" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv16" name="Keqv16" value="0.25" units="dimensionless"/>
                <parameter id="KADPv16" name="KADPv16" value="0.11" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vG6PDH" name="Glucose 6-phosphate dehydrogenase" fast="false">
            <listOfReactants>
              <speciesReference species="Glc6P"/>
              <speciesReference species="NADPf"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="MgATP"/>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GlcA6P"/>
              <speciesReference species="NADPHf"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="MgATP"/>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <apply>
                          <divide/>
                          <ci> Vmaxv17 </ci>
                          <ci> KG6Pv17 </ci>
                        </apply>
                        <ci> KNADPv17 </ci>
                      </apply>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> Glc6P </ci>
                          <ci> NADPf </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> GlcA6P </ci>
                            <ci> NADPHf </ci>
                          </apply>
                          <ci> Keqv17 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <cn type="integer"> 1 </cn>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> NADPf </ci>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> Glc6P </ci>
                              <ci> KG6Pv17 </ci>
                            </apply>
                          </apply>
                        </apply>
                        <ci> KNADPv17 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <plus/>
                          <ci> ATPf </ci>
                          <ci> MgATP </ci>
                        </apply>
                        <ci> KATPv17 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <ci> NADPHf </ci>
                        <ci> KNADPHv17 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <plus/>
                          <ci> Gri23P2f </ci>
                          <ci> MgGri23P2 </ci>
                        </apply>
                        <ci> KPGA23v17 </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv17" name="Vmaxv17" value="162" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KG6Pv17" name="KG6Pv17" value="0.0667" units="MWUSERUNIT_mM"/>
                <parameter id="KNADPv17" name="KNADPv17" value="0.00367" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv17" name="Keqv17" value="2000" units="dimensionless"/>
                <parameter id="KATPv17" name="KATPv17" value="0.749" units="MWUSERUNIT_mM"/>
                <parameter id="KNADPHv17" name="KNADPHv17" value="0.00312" units="MWUSERUNIT_mM"/>
                <parameter id="KPGA23v17" name="KPGA23v17" value="2.289" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPGLDH" name="Phosphogluconate dehydrogenase" fast="false">
            <listOfReactants>
              <speciesReference species="GlcA6P"/>
              <speciesReference species="NADPf"/>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="MgATP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Rul5P"/>
              <speciesReference species="NADPHf"/>
              <speciesReference species="Gri23P2f"/>
              <speciesReference species="MgGri23P2"/>
              <speciesReference species="ATPf"/>
              <speciesReference species="MgATP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <apply>
                          <divide/>
                          <ci> Vmaxv18 </ci>
                          <ci> K6PG1v18 </ci>
                        </apply>
                        <ci> KNADPv18 </ci>
                      </apply>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> GlcA6P </ci>
                          <ci> NADPf </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> Rul5P </ci>
                            <ci> NADPHf </ci>
                          </apply>
                          <ci> Keqv18 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> NADPf </ci>
                            <ci> KNADPv18 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> GlcA6P </ci>
                            <ci> K6PG1v18 </ci>
                          </apply>
                          <apply>
                            <divide/>
                            <apply>
                              <plus/>
                              <ci> Gri23P2f </ci>
                              <ci> MgGri23P2 </ci>
                            </apply>
                            <ci> KPGA23v18 </ci>
                          </apply>
                        </apply>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <plus/>
                          <ci> ATPf </ci>
                          <ci> MgATP </ci>
                        </apply>
                        <ci> KATPv18 </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> NADPHf </ci>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> GlcA6P </ci>
                              <ci> K6PG2v18 </ci>
                            </apply>
                          </apply>
                        </apply>
                        <ci> KNADPHv18 </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv18" name="Vmaxv18" value="1575" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="K6PG1v18" name="K6PG1v18" value="0.01" units="MWUSERUNIT_mM"/>
                <parameter id="KNADPv18" name="KNADPv18" value="0.018" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv18" name="Keqv18" value="141.7" units="dimensionless"/>
                <parameter id="KPGA23v18" name="KPGA23v18" value="0.12" units="MWUSERUNIT_mM"/>
                <parameter id="KATPv18" name="KATPv18" value="0.154" units="MWUSERUNIT_mM"/>
                <parameter id="K6PG2v18" name="K6PG2v18" value="0.058" units="MWUSERUNIT_mM"/>
                <parameter id="KNADPHv18" name="KNADPHv18" value="0.0045" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vGSSGRD" name="Glutathione reductase" fast="false">
            <listOfReactants>
              <speciesReference species="GSSG"/>
              <speciesReference species="NADPHf"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GSH" stoichiometry="2"/>
              <speciesReference species="NADPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv19 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> GSSG </ci>
                            <ci> NADPHf </ci>
                          </apply>
                          <apply>
                            <times/>
                            <ci> KGSSGv19 </ci>
                            <ci> KNADPHv19 </ci>
                          </apply>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <apply>
                              <divide/>
                              <apply>
                                <power/>
                                <ci> GSH </ci>
                                <cn type="integer"> 2 </cn>
                              </apply>
                              <apply>
                                <power/>
                                <ci> KGSHv19 </ci>
                                <cn type="integer"> 2 </cn>
                              </apply>
                            </apply>
                            <ci> NADPf </ci>
                          </apply>
                          <apply>
                            <times/>
                            <ci> KNADPv19 </ci>
                            <ci> Keqv19 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <cn type="integer"> 1 </cn>
                      <apply>
                        <divide/>
                        <apply>
                          <times/>
                          <ci> NADPHf </ci>
                          <apply>
                            <plus/>
                            <cn type="integer"> 1 </cn>
                            <apply>
                              <divide/>
                              <ci> GSSG </ci>
                              <ci> KGSSGv19 </ci>
                            </apply>
                          </apply>
                        </apply>
                        <ci> KNADPHv19 </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <divide/>
                          <ci> NADPf </ci>
                          <ci> KNADPv19 </ci>
                        </apply>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <apply>
                              <times/>
                              <ci> GSH </ci>
                              <apply>
                                <plus/>
                                <cn type="integer"> 1 </cn>
                                <apply>
                                  <divide/>
                                  <ci> GSH </ci>
                                  <ci> KGSHv19 </ci>
                                </apply>
                              </apply>
                            </apply>
                            <ci> KGSHv19 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv19" name="Vmaxv19" value="90" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="KGSSGv19" name="KGSSGv19" value="0.0652" units="MWUSERUNIT_mM"/>
                <parameter id="KNADPHv19" name="KNADPHv19" value="0.00852" units="MWUSERUNIT_mM"/>
                <parameter id="KGSHv19" name="KGSHv19" value="20" units="MWUSERUNIT_mM"/>
                <parameter id="KNADPv19" name="KNADPv19" value="0.07" units="MWUSERUNIT_mM"/>
                <parameter id="Keqv19" name="Keqv19" value="1.04" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vGSHox" name="Glutathione oxidation" fast="false">
            <listOfReactants>
              <speciesReference species="GSH" stoichiometry="2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GSSG"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> Kv20 </ci>
                  <ci> GSH </ci>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Kv20" name="Kv20" value="0.03" units="MWUSERUNIT_hour_inverse"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vRibPepi" name="Phosphoribulose epimerase" fast="false">
            <listOfReactants>
              <speciesReference species="Rul5P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Xul5P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv21 </ci>
                      <apply>
                        <minus/>
                        <ci> Rul5P </ci>
                        <apply>
                          <divide/>
                          <ci> Xul5P </ci>
                          <ci> Keqv21 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> Rul5P </ci>
                      <apply>
                        <times/>
                        <ci> KRu5Pv21 </ci>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> Xul5P </ci>
                            <ci> KX5Pv21 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv21" name="Vmaxv21" value="4634" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv21" name="Keqv21" value="2.7" units="dimensionless"/>
                <parameter id="KRu5Pv21" name="KRu5Pv21" value="0.19" units="MWUSERUNIT_mM"/>
                <parameter id="KX5Pv21" name="KX5Pv21" value="0.5" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vRibPiso" name="Ribose phosphate isomerase" fast="false">
            <listOfReactants>
              <speciesReference species="Rul5P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Rib5P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv22 </ci>
                      <apply>
                        <minus/>
                        <ci> Rul5P </ci>
                        <apply>
                          <divide/>
                          <ci> Rib5P </ci>
                          <ci> Keqv22 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <ci> Rul5P </ci>
                      <apply>
                        <times/>
                        <ci> KRu5Pv22 </ci>
                        <apply>
                          <plus/>
                          <cn type="integer"> 1 </cn>
                          <apply>
                            <divide/>
                            <ci> Rib5P </ci>
                            <ci> KR5Pv22 </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv22" name="Vmaxv22" value="730" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv22" name="Keqv22" value="3" units="dimensionless"/>
                <parameter id="KRu5Pv22" name="KRu5Pv22" value="0.78" units="MWUSERUNIT_mM"/>
                <parameter id="KR5Pv22" name="KR5Pv22" value="2.2" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vTrKet1" name="Transketolase 1" fast="false">
            <listOfReactants>
              <speciesReference species="Xul5P"/>
              <speciesReference species="Rib5P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GraP"/>
              <speciesReference species="Sed7P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv23 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> Rib5P </ci>
                          <ci> Xul5P </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> GraP </ci>
                            <ci> Sed7P </ci>
                          </apply>
                          <ci> Keqv23 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K1v23 </ci>
                          <ci> Rib5P </ci>
                        </apply>
                        <ci> Xul5P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K2v23 </ci>
                          <apply>
                            <times/>
                            <ci> K6v23 </ci>
                            <ci> Sed7P </ci>
                          </apply>
                        </apply>
                        <ci> Rib5P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K3v23 </ci>
                          <apply>
                            <times/>
                            <ci> K5v23 </ci>
                            <ci> Sed7P </ci>
                          </apply>
                        </apply>
                        <ci> GraP </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> K4v23 </ci>
                        <ci> Sed7P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> K7v23 </ci>
                        <ci> Xul5P </ci>
                        <ci> GraP </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv23" name="Vmaxv23" value="23.5" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv23" name="Keqv23" value="1.05" units="dimensionless"/>
                <parameter id="K1v23" name="K1v23" value="0.4177" units="MWUSERUNIT_mM"/>
                <parameter id="K2v23" name="K2v23" value="0.3055" units="MWUSERUNIT_mM"/>
                <parameter id="K6v23" name="K6v23" value="0.00774" units="dimensionless"/>
                <parameter id="K3v23" name="K3v23" value="12.432" units="MWUSERUNIT_mM"/>
                <parameter id="K5v23" name="K5v23" value="0.41139" units="dimensionless"/>
                <parameter id="K4v23" name="K4v23" value="0.00496" units="MWUSERUNIT_mM"/>
                <parameter id="K7v23" name="K7v23" value="48.8" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vTrAld" name="Transaldolase" fast="false">
            <listOfReactants>
              <speciesReference species="GraP"/>
              <speciesReference species="Sed7P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="E4P"/>
              <speciesReference species="Fru6P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv24 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> Sed7P </ci>
                          <ci> GraP </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> E4P </ci>
                            <ci> Fru6P </ci>
                          </apply>
                          <ci> Keqv24 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K1v24 </ci>
                          <ci> GraP </ci>
                        </apply>
                        <ci> Sed7P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K2v24 </ci>
                          <apply>
                            <times/>
                            <ci> K6v24 </ci>
                            <ci> Fru6P </ci>
                          </apply>
                        </apply>
                        <ci> GraP </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K3v24 </ci>
                          <apply>
                            <times/>
                            <ci> K5v24 </ci>
                            <ci> Fru6P </ci>
                          </apply>
                        </apply>
                        <ci> E4P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> K4v24 </ci>
                        <ci> Fru6P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> K7v24 </ci>
                        <ci> Sed7P </ci>
                        <ci> E4P </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv24" name="Vmaxv24" value="27.2" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv24" name="Keqv24" value="1.05" units="dimensionless"/>
                <parameter id="K1v24" name="K1v24" value="0.00823" units="MWUSERUNIT_mM"/>
                <parameter id="K2v24" name="K2v24" value="0.04765" units="MWUSERUNIT_mM"/>
                <parameter id="K6v24" name="K6v24" value="0.4653" units="dimensionless"/>
                <parameter id="K3v24" name="K3v24" value="0.1733" units="MWUSERUNIT_mM"/>
                <parameter id="K5v24" name="K5v24" value="0.8683" units="dimensionless"/>
                <parameter id="K4v24" name="K4v24" value="0.006095" units="MWUSERUNIT_mM"/>
                <parameter id="K7v24" name="K7v24" value="2.524" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPPRPPS" name="Phosphoribosylpyrophosphate synthetase" fast="false">
            <listOfReactants>
              <speciesReference species="MgATP"/>
              <speciesReference species="Rib5P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="MgAMP"/>
              <speciesReference species="PRPP"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv25 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> Rib5P </ci>
                          <ci> MgATP </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> PRPP </ci>
                            <ci> MgAMP </ci>
                          </apply>
                          <ci> Keqv25 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <times/>
                      <apply>
                        <plus/>
                        <ci> KATPv25 </ci>
                        <ci> MgATP </ci>
                      </apply>
                      <apply>
                        <plus/>
                        <ci> KR5Pv25 </ci>
                        <ci> Rib5P </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv25" name="Vmaxv25" value="1.1" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv25" name="Keqv25" value="0.001" units="dimensionless"/>
                <parameter id="KATPv25" name="KATPv25" value="0.03" units="MWUSERUNIT_mM"/>
                <parameter id="KR5Pv25" name="KR5Pv25" value="0.57" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vTrKet2" name="Transketolase 2" fast="false">
            <listOfReactants>
              <speciesReference species="Xul5P"/>
              <speciesReference species="E4P"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="GraP"/>
              <speciesReference species="Fru6P"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <ci> Vmaxv26 </ci>
                      <apply>
                        <minus/>
                        <apply>
                          <times/>
                          <ci> E4P </ci>
                          <ci> Xul5P </ci>
                        </apply>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> GraP </ci>
                            <ci> Fru6P </ci>
                          </apply>
                          <ci> Keqv26 </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K1v26 </ci>
                          <ci> E4P </ci>
                        </apply>
                        <ci> Xul5P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K2v26 </ci>
                          <apply>
                            <times/>
                            <ci> K6v26 </ci>
                            <ci> Fru6P </ci>
                          </apply>
                        </apply>
                        <ci> E4P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <apply>
                          <plus/>
                          <ci> K3v26 </ci>
                          <apply>
                            <times/>
                            <ci> K5v26 </ci>
                            <ci> Fru6P </ci>
                          </apply>
                        </apply>
                        <ci> GraP </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> K4v26 </ci>
                        <ci> Fru6P </ci>
                      </apply>
                      <apply>
                        <times/>
                        <ci> K7v26 </ci>
                        <ci> Xul5P </ci>
                        <ci> GraP </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv26" name="Vmaxv26" value="23.5" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="Keqv26" name="Keqv26" value="1.2" units="dimensionless"/>
                <parameter id="K1v26" name="K1v26" value="0.00184" units="MWUSERUNIT_mM"/>
                <parameter id="K2v26" name="K2v26" value="0.3055" units="MWUSERUNIT_mM"/>
                <parameter id="K6v26" name="K6v26" value="0.122" units="dimensionless"/>
                <parameter id="K3v26" name="K3v26" value="0.0548" units="MWUSERUNIT_mM"/>
                <parameter id="K5v26" name="K5v26" value="0.0287" units="dimensionless"/>
                <parameter id="K4v26" name="K4v26" value="0.0003" units="MWUSERUNIT_mM"/>
                <parameter id="K7v26" name="K7v26" value="0.215" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vMgATP" name="MgATP dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="MgATP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Mgf"/>
              <speciesReference species="ATPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> EqMult </ci>
                  <apply>
                    <minus/>
                    <ci> MgATP </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> Mgf </ci>
                        <ci> ATPf </ci>
                      </apply>
                      <ci> KdATP </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="EqMult" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="KdATP" name="KdATP" value="0.072" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vMgADP" name="MgADP dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="MgADP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Mgf"/>
              <speciesReference species="ADPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMult1c7398f8_ec08_499d_9cb5_a94bf37bf5de </ci>
                  <apply>
                    <minus/>
                    <ci> MgADP </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> Mgf </ci>
                        <ci> ADPf </ci>
                      </apply>
                      <ci> KdADP </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMult1c7398f8_ec08_499d_9cb5_a94bf37bf5de" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="KdADP" name="KdADP" value="0.76" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vMgAMP" name="MgAMP dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="MgAMP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Mgf"/>
              <speciesReference species="AMPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMult7bc05da0_57a2_4fcb_97e4_0a4125b200a9 </ci>
                  <apply>
                    <minus/>
                    <ci> MgAMP </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> Mgf </ci>
                        <ci> AMPf </ci>
                      </apply>
                      <ci> KdAMP </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMult7bc05da0_57a2_4fcb_97e4_0a4125b200a9" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="KdAMP" name="KdAMP" value="16.64" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vMgGri23P2" name="MgGri23P2 dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="MgGri23P2"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Mgf"/>
              <speciesReference species="Gri23P2f"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMult40e16824_df18_4b7c_9819_3aa02e325d37 </ci>
                  <apply>
                    <minus/>
                    <ci> MgGri23P2 </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> Mgf </ci>
                        <ci> Gri23P2f </ci>
                      </apply>
                      <ci> Kd23P2G </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMult40e16824_df18_4b7c_9819_3aa02e325d37" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Kd23P2G" name="Kd23P2G" value="1.667" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vP1NADP" name="P1NADP dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="P1NADP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="P1f"/>
              <speciesReference species="NADPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMult4defd00e_3279_4687_b82e_7b916e5112f0 </ci>
                  <apply>
                    <minus/>
                    <ci> P1NADP </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> P1f </ci>
                        <ci> NADPf </ci>
                      </apply>
                      <ci> Kd1 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMult4defd00e_3279_4687_b82e_7b916e5112f0" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Kd1" name="Kd1" value="0.0002" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vP1NADPH" name="P1NADPH dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="P1NADPH"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="P1f"/>
              <speciesReference species="NADPHf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMult2af27f25_b2d2_4428_939e_cea461ef0b24 </ci>
                  <apply>
                    <minus/>
                    <ci> P1NADPH </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> P1f </ci>
                        <ci> NADPHf </ci>
                      </apply>
                      <ci> Kd3 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMult2af27f25_b2d2_4428_939e_cea461ef0b24" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Kd3" name="Kd3" value="1e-05" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vP2NADP" name="P2NADP dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="P2NADP"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="P2f"/>
              <speciesReference species="NADPf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMultb1345c91_6ce7_4cbf_a786_988a358ef818 </ci>
                  <apply>
                    <minus/>
                    <ci> P2NADP </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> P2f </ci>
                        <ci> NADPf </ci>
                      </apply>
                      <ci> Kd2 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMultb1345c91_6ce7_4cbf_a786_988a358ef818" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Kd2" name="Kd2" value="1e-05" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vP2NADPH" name="P2NADPH dissociation" fast="false">
            <listOfReactants>
              <speciesReference species="P2NADPH"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="P2f"/>
              <speciesReference species="NADPHf"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> mwEqMultc26a820a_899a_4546_b91d_a2861f5380a4 </ci>
                  <apply>
                    <minus/>
                    <ci> P2NADPH </ci>
                    <apply>
                      <divide/>
                      <apply>
                        <times/>
                        <ci> P2f </ci>
                        <ci> NADPHf </ci>
                      </apply>
                      <ci> Kd4 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mwEqMultc26a820a_899a_4546_b91d_a2861f5380a4" name="EqMult" value="10000000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Kd4" name="Kd4" value="0.0002" units="MWUSERUNIT_mM"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="mw634af25f_4457_4db4_b867_c6436097cc2f" name="Glucose transport" fast="false">
            <listOfReactants>
              <speciesReference species="mw7466adf7_85fd_472f_bf01_8f68b970cb4f"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Glcin"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <apply>
                    <divide/>
                    <apply>
                      <times/>
                      <apply>
                        <divide/>
                        <ci> mw9ed9c8a9_6993_489f_8b5c_ef23a6a30b44 </ci>
                        <ci> mwba6d6446_2e57_458a_a2f9_c92dfa30363e </ci>
                      </apply>
                      <apply>
                        <minus/>
                        <ci> mw7466adf7_85fd_472f_bf01_8f68b970cb4f </ci>
                        <apply>
                          <divide/>
                          <ci> Glcin </ci>
                          <ci> mwafba4267_136b_4e40_aeee_72d56deef8ae </ci>
                        </apply>
                      </apply>
                    </apply>
                    <apply>
                      <plus/>
                      <cn type="integer"> 1 </cn>
                      <apply>
                        <divide/>
                        <ci> mw7466adf7_85fd_472f_bf01_8f68b970cb4f </ci>
                        <ci> mwba6d6446_2e57_458a_a2f9_c92dfa30363e </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <ci> Glcin </ci>
                        <ci> mw5e3617e6_ed62_4a20_82d6_9024848199ec </ci>
                      </apply>
                      <apply>
                        <divide/>
                        <apply>
                          <divide/>
                          <apply>
                            <times/>
                            <ci> mw4166bafa_fe97_4b80_a66f_c7efb516aaf8 </ci>
                            <ci> mw7466adf7_85fd_472f_bf01_8f68b970cb4f </ci>
                            <ci> Glcin </ci>
                          </apply>
                          <ci> mwba6d6446_2e57_458a_a2f9_c92dfa30363e </ci>
                        </apply>
                        <ci> mw5e3617e6_ed62_4a20_82d6_9024848199ec </ci>
                      </apply>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="mw9ed9c8a9_6993_489f_8b5c_ef23a6a30b44" name="Vmaxv0" value="33.6" units="MWUSERUNIT_mM_per_hour"/>
                <parameter id="mwba6d6446_2e57_458a_a2f9_c92dfa30363e" name="KMoutv0" value="1.7" units="MWUSERUNIT_mM"/>
                <parameter id="mwafba4267_136b_4e40_aeee_72d56deef8ae" name="Keqv0" value="1" units="dimensionless"/>
                <parameter id="mw5e3617e6_ed62_4a20_82d6_9024848199ec" name="KMinv0" value="6.9" units="MWUSERUNIT_mM"/>
                <parameter id="mw4166bafa_fe97_4b80_a66f_c7efb516aaf8" name="alfav0" value="0.54" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPhiexch" name="Phosphate exchange" fast="false">
            <listOfReactants>
              <speciesReference species="mwfe0bb4bb_890b_44f4_af0c_a3168bb257e9"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Phi"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> Vmaxv27 </ci>
                  <apply>
                    <minus/>
                    <ci> mwfe0bb4bb_890b_44f4_af0c_a3168bb257e9 </ci>
                    <apply>
                      <divide/>
                      <ci> Phi </ci>
                      <ci> Keqv27 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv27" name="Vmaxv27" value="100" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Keqv27" name="Keqv27" value="1" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vLacexch" name="Lactate exchange" fast="false">
            <listOfReactants>
              <speciesReference species="mw8c5690e1_b876_4c4d_bc4e_d34e76b52173"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Lac"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> Vmaxv28 </ci>
                  <apply>
                    <minus/>
                    <ci> mw8c5690e1_b876_4c4d_bc4e_d34e76b52173 </ci>
                    <apply>
                      <divide/>
                      <ci> Lac </ci>
                      <ci> Keqv28 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv28" name="Vmaxv28" value="10000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Keqv28" name="Keqv28" value="1" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
          <reaction id="vPyrexch" name="Pyruvate exchange" fast="false">
            <listOfReactants>
              <speciesReference species="mw3f64eb09_4a72_4b60_b7f2_68a118caaf7a"/>
            </listOfReactants>
            <listOfProducts>
              <speciesReference species="Pyr"/>
            </listOfProducts>
            <kineticLaw>
              <math xmlns="http://www.w3.org/1998/Math/MathML">
                <apply>
                  <times/>
                  <ci> mw21d4d476_8151_49e5_8afc_b187ec173e51 </ci>
                  <ci> Vmaxv29 </ci>
                  <apply>
                    <minus/>
                    <ci> mw3f64eb09_4a72_4b60_b7f2_68a118caaf7a </ci>
                    <apply>
                      <divide/>
                      <ci> Pyr </ci>
                      <ci> Keqv29 </ci>
                    </apply>
                  </apply>
                </apply>
              </math>
              <listOfParameters>
                <parameter id="Vmaxv29" name="Vmaxv29" value="10000" units="MWUSERUNIT_hour_inverse"/>
                <parameter id="Keqv29" name="Keqv29" value="1" units="dimensionless"/>
              </listOfParameters>
            </kineticLaw>
          </reaction>
        </listOfReactions>
      </model>
    </sbml>
