locally weighted-regression using linear least-squares

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In my research, I am trying to process some biological signals and I was seeing a paper that does locally weighted-regression using linear least-squares on time domains signals. I am completely new to the topic and would like to know where to get started or if there are any matlab algorithms I could use for this.
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Torsten
Torsten on 17 Mar 2022
This seems to be the right mathematical tool, but don't ask me about the relation with the physics behind your problem.

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