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6.6 GB mat file load error with MATLAB 2014b: Error using load Cannot read file

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I saved a 6.6 GB mat file with MATLAB 2014b previously and now I need to open it with the same computer and the same version of MATLAB.
I clicked the "open" button under the "HOME" tab in the MATLAB window and found the mat file and "open". However, MATLAB gave me this:
Error using load Cannot read file D:\MATLAB & Simulink Simulation Results\XXX\XXX.mat.
I tried to change the path but it could not work.
Do you know how can I load the large mat file to the workspace?
Thank you in advance!

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