Optimum input to minimise a result matrix
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I have a 100+ test that shows me a qualitiy of a process.
For one test, there is an input (4x150) and as a result there is a matrix(260x260) that shows process quality. I want to minimize the result matrix(minimum is desired, means more quality).
To improve result matrix, I want to develop an algorithm that process all 100+ test data with input and output and show me best input for desired result(minimum matrix).
Is it possible, which tool should I use ?
I know the question is too generic, any help will be appreciated.