GTOM - Generalized Topological Overlaping Measure

Efficient implementation of the Generalized Topological Overlaping Measure (GTOM)

COMPUTEGTOM computes the generalized overlaping measure algorithm (GTOM) [1]

Authors
Joaquin Goñi <[e-mail]>
&
Iñigo Martincorena <[e-mail]>

University of Navarra -
Dpt. of Physics and Applied Mathematics &
Centre for Applied Medical Research. Pamplona (Spain).

November 22nd, 2007

batchComputeGTOM.m contains an example that loads and adjacency matrix and computes the GTOM matrix. Finally, a hierarchical clustering of GTOM matrix is carried out.

Type 'help computeGTOM' for further information and examples.

References
GTOM [1] Yip A, Horvath S (2007) Gene network interconnectedness and the generalized topological overlap measure BMC Bioinformatics 2007, 8:22
TOM [2] Ravasz E. et al. (2002) Hierarchical Organization of Modularity in Metabolic Networks Science 297 (5586), 1551.