Retinal Vessel Tortuosity Analysis

This script is for calculating multiple retinal vessel tortuosity measure such as Vessel Torttousity Index (VTI)


Updated 5 Dec 2019

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This script is for quantification of retinal vessel tortuosity in fundus/OPTOS images. Several measures of tortuosity is calculated and saved in an excel file. Tortuosity measures are based on vessel centerline within a circumpapillary region centered on the optic nerve head (ONH). The user needs to select the center of ONH and its diameter. Also, the user can modify thresholds for vessel segmentation. Additionally, the user needs to select endpoints of each vessel for extracting the centerline and calculating its tortuosity.
Please see the user manual Retinal Vessel Tortuosity.pdf for further instruction.

Cite As

Maz M. Khansari (2023). Retinal Vessel Tortuosity Analysis (, MATLAB Central File Exchange. Retrieved .

Khansari, Maziyar M., et al. “Method for Quantitative Assessment of Retinal Vessel Tortuosity in Optical Coherence Tomography Angiography Applied to Sickle Cell Retinopathy.” Biomedical Optics Express, vol. 8, no. 8, The Optical Society, July 2017, p. 3796, doi:10.1364/boe.8.003796.

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MATLAB Release Compatibility
Created with R2017a
Compatible with R2014a to R2019b
Platform Compatibility
Windows macOS Linux
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