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Herr Klaus

by Klaus Zorn-Pauly

 

20 Sep 2002 (Updated 24 Sep 2002)

Simulink implementation of a human atrial action potential model (Nygren et al.)

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Simulink implementation of a human atrial action potential model based on the publication of:
A Nygren, C. Fiset, L. Firek, J.W. Clark, D.S. Lindblad, R.B. Clark and W.R. Giles. Mathematical Model of an Adult Human Atrial Cell: The Role of K+ Currents in Repolarization. Circulation Research 1998; 82: 63-81.

Simulation can be done easiest in Simulink with (simulation: start). The time course of the action potential can be seen in the workspace with the command plot(t,v). For other parameters of the model the to workspace blocks have to be connected to the appropriate blocks.
To change the stimulus current the parameters of the pulse generator named stimulus (inside the subsystem sarcolemmal currents) have to be changed. Thus you can experience supra/ super-threshold stimulation of the model cell.

Required Products Simulink
MATLAB release MATLAB 6.1 (R12.1)
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Comments and Ratings (6)
11 Aug 2006 Richard Boyle

An excellent model, very useful!

06 Aug 2007 Dit Papa Lamine ndao

glad to know a cardiac modeler like me
1)type cardiorythmor on google
2)patent 1:mecanic cardiac simulator called cardiorythmor,2005,www.inpi.fr,N°Fr0402721
2)patent 2:artificial heart VI1,2005,www.inpi.fr,N°Fr0405909

04 Sep 2007 IGOR KOGHEMAK  
18 Jan 2008 Abbas kader

happy to find a good Physiological Modeler , you made a good job

07 Feb 2008 Erez Somech

WOW, an amazing model! SUPER.

20 May 2011 Hugo Juarez

I really like your job! Very useful

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Tag Activity for this File
Tag Applied By Date/Time
medical Klaus Zorn-Pauly 22 Oct 2008 06:51:47
action potential Klaus Zorn-Pauly 22 Oct 2008 06:51:47
human atrial cell Klaus Zorn-Pauly 22 Oct 2008 06:51:47
simulation Klaus Zorn-Pauly 22 Oct 2008 06:51:47

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