Ghrelin mathematical modeling

On this code you shall find a matlab code for simulating the ghrelin dynamics coming from foodstuff
Updated 26 Feb 2018

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Ghrelin is a quite powerful orexigenic hormone discovered in the late 1990s that controls appetite and energy homeostasis, alongside leptin and other hormones still to be investigated in depth by the medical sciences literature. Accordingly, we provide a (simple) mathematical model, consisting of a set of ordinary differential equations detailing ghrelin dynamics combined to gastrointestinal signals due to meals [2].
This code was created for studying the ghrelin dynamics [1].
Changing the internal parameters, defined in the code, you can arrive to some behaviors.
You have two codes:
* model_1: the ghrelin dynamics [1];
* Main: the script where parameters are defined, the main script, run this one;
Should you decide to use the code in your research, please, cite the paper [1]. You may want to take a look at [2].
Please, send feedbacks to


1. J.G. Pires, A. Borri, A. De Gaetano, C. Manes, P. Palumbo. A short-term dynamical model for ghrelin. IFAC 2017.;
2. J.G. Pires (2017), Mathematical modeling in energy homeostasis, appetite control and food intake with a special attention to ghrelin, PhD thesis, Department of Information Engineering, Computer Science and Mathematics, University of L'Aquila.

Alternative usages of this code:

- Exercise on numerical simulations of ordinary differential equations;
- Example of mathematical biology like modeling and simulations;
- Training/first glimpse on appetite and food intake control;

Cite As

Jorge G Pires (2024). Ghrelin mathematical modeling (, MATLAB Central File Exchange. Retrieved .

MATLAB Release Compatibility
Created with R2014b
Compatible with any release
Platform Compatibility
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Ghrelin dynamics/

Version Published Release Notes

It was missing the model_1 file, needed for the numerical simulations.
Adding some space in the main text

Link to PhD thesis