Bispecific Protein Degrader PK-PD Model for SimBiology
SimBiology project file for a published PK-PD model for bispecific protein degraders
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The SimBiology model described in the following publication:
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
Please note that some of the included visualizations require the "gridfit" routine written by John D'Errico: Surface Fitting using gridfit (https://www.mathworks.com/matlabcentral/fileexchange/8998-surface-fitting-using-gridfit), MATLAB Central File Exchange.
Cite As
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
General Information
- Version 1.0.2 (161 KB)
MATLAB Release Compatibility
- Compatible with R2022a and later releases
Platform Compatibility
- Windows
- macOS
- Linux
Communities
More Files in the SimBiology Community
| Version | Published | Release Notes | Action |
|---|---|---|---|
| 1.0.2 | Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology. |
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| 1.0.1 | Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology. |
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| 1.0.0 |
