SimBiology model for Target-Mediated Drug Disposition (TMDD)

SimBiology implementation of the Target-Mediated Drug Disposition (TMDD) model

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This is the SimBiology implementation of generic Target-Mediated Drug Disposition model (TMDD) presented in [1].
Reference:
[1] Mager DE and Jusko WJ (2001) General pharmacokinetic model for drugs exhibiting target-mediated drug disposition. J Pharmacokinetics and Pharmacodynamics 28: 507–532.

Cite As

Fulden Buyukozturk (2026). SimBiology model for Target-Mediated Drug Disposition (TMDD) (https://www.mathworks.com/matlabcentral/fileexchange/32926-simbiology-model-for-target-mediated-drug-disposition-tmdd), MATLAB Central File Exchange. Retrieved .

General Information

MATLAB Release Compatibility

  • Compatible with R2020b and later releases

Platform Compatibility

  • Windows
  • macOS
  • Linux
Communities
More Files in the  SimBiology Community
Version Published Release Notes Action
1.0.1.2

Updated release compatibility

1.0.1.1

Updated release compatibility.

1.0.1

- Updated to work with newer versions of SimBiology.
- Added a Dose to model a daily dosing schedule and updated the scan program accordingly.

1.0.0.1

Updated license

1.0.0.0