Generic SimBiology PBPK model

SimBiology implementation of a generic PBPK model. Human fasted, Human fed and Rat physiologies.

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Cite As

MathWorks SimBiology Team (2026). Generic SimBiology PBPK model (https://www.mathworks.com/matlabcentral/fileexchange/37752-generic-simbiology-pbpk-model), MATLAB Central File Exchange. Retrieved .

Acknowledgements

Inspired: Diagnostic PBPK model for S100B

General Information

MATLAB Release Compatibility

  • Compatible with any release

Platform Compatibility

  • Windows
  • macOS
  • Linux
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Version Published Release Notes Action
1.2.1

Updated description to include instructions to add the folder to MATLAB path.

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1.2.1-0

Included Plasma and Blood concentrations
Changed Ktransit = 0.693/TransitTime to Ktransit = 1/TransitTime
Changed transit rate normalizations small intestine from Ktransit_i = Ktransit*length_i/length_tot to Ktransit_i = Ktransit*length_tot/length_i

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1.2.0

Correct modeling errors associated with volume corrections.

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1.1.0

Updated license

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1.1.0-0

Updated Screenshot

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1.0.0

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