Preclinical PKPD modeling

Classes for fundamental PKPD modeling in drug discovery (no support for a NLME modeling).

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Cite As

Peter Gennemark (2026). Preclinical PKPD modeling (https://www.mathworks.com/matlabcentral/fileexchange/43521-preclinical-pkpd-modeling), MATLAB Central File Exchange. Retrieved .

General Information

MATLAB Release Compatibility

  • Compatible with any release

Platform Compatibility

  • Windows
  • macOS
  • Linux
Version Published Release Notes Action
1.6.0

Three-comparment PK model, and PD turnover models added.
Steady-state analytical solutions to 1, 2 and 3-compartment models added (PK_[1,2,3]comp_Ka_Cl_fun_SS.m)
Estimation using maximum liklihood added, see example_fit_loglikelihood.m

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1.5.0

Several new PD models (e.g. PD turnover models)
One new example
Ensured feasibility for Matlab R2014a

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1.4.0

Added reference to published paper

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1.3.0

PK_2comp_Ka_Cl_ode was updated.

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1.2.0

2013-10-25: corrected calculation of coefficient of variation in Model.m. Revised example_readExcel_PKPD_writePowerPoint.m to improve readability.

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1.0.0

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