Tissue Thickness Estimation via Minimum Line Integrals

Codes for tissue thickness estimation from 3D images, using a minimum-line-integral approach.

https://www.nitrc.org/projects/thickness

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This toolbox can be used to compute the tissue thickness, such as the cortical thickness, from soft-segmented 3D medical images (tissue probability maps) via a volumetric approach based on minimum line integrals (Aganj et al, HBM 2009).

For a short tutorial, see EXAMPLE.m.

Cite As

Iman Aganj (2026). Tissue Thickness Estimation via Minimum Line Integrals (https://www.mathworks.com/matlabcentral/fileexchange/64085-tissue-thickness-estimation-via-minimum-line-integrals), MATLAB Central File Exchange. Retrieved .

I. Aganj, G. Sapiro, N. Parikshak, S. K. Madsen, and P. Thompson, “Measurement of cortical thickness from MRI by minimum line integrals on soft-classified tissue,” Human Brain Mapping, vol. 30, no. 10, pp. 3188–3199, 2009. http://doi.org/10.1002/hbm.20740

General Information

MATLAB Release Compatibility

  • Compatible with any release

Platform Compatibility

  • Windows
  • macOS
  • Linux
Version Published Release Notes Action
1.3.0.1

Minor update.

1.3.0.0

Compiled MEX files removed. Download them at: www.nitrc.org/projects/thickness

1.1.0.0

Minor edits.

1.0.0.0