DARPS2

Discrete Asexually Reproducing Population Simulator 2
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Updated 7 Feb 2022

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This is the DARPS2.m source code used to run simulations for the following paper:
Small-Saunders JL, Hagenah LM, Wicht KJ, Dhingra SK, Deni I, Kim J, et al. (2022). Evidence for the early emergence of piperaquineresistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance. PLoS Pathog 18(2): e1010278. https://doi.org/10.1371/journal.ppat.1010278
4 source files are included:
1) DARPS2.m: this is the main population simulator
2) ComputeNetRelativeGrowthRates.m: this defines the growth rate parameters for the specific strains in the PLoS Pathogens paper
3) SampleDARPS2Driver.m: this demonstrates a single call to DARPS2 using the parameters specified.
4) SampleDARPS2BatchDriver.m: this demonstrates a series of calls to DARPS2 under various treatment regimes.

Cite As

Margaret J. Eppstein (2021). DARPS2 (https://www.mathworks.com/matlabcentral/fileexchange/89321-darps2), MATLAB Central File Exchange.

Small-Saunders JL, Hagenah LM, Wicht KJ, Dhingra SK, Deni I, Kim J, et al. (2022). Evidence for the early emergence of piperaquineresistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance. PLoS Pathog 18(2): e1010278. https://doi.org/10.1371/journal.ppat.1010278

MATLAB Release Compatibility
Created with R2021a
Compatible with any release
Platform Compatibility
Windows macOS Linux
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Version Published Release Notes
1.0.3

I added the correct citation for the published paper that uses this code.

1.0.2

This version include the actual growth rate data for the strains used in our PLoS Pathogens paper (see citation below).

1.0.1

I corrected the URL in the citation.

1.0.0