IMWRITE supports multipage TIFF files as the following example illustrates:
a = imread('peppers.png');
imwrite(rgb2gray(a), 'myFile.TIFF', 'writemode', 'append')
Hence, IMWRITE will write the images on a single page one above the other. We use "append" parameter to do this. When using IMREAD to read the same image, you could use indexing as described in the documentation, to read the various images aligned by IMWRITE.
For example, the following commands would read and display both the frames from myFile.TIFF.